Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype
about
Mutational analyses of the signals involved in the subcellular location of DSCR1.Down syndrome: searching for the genetic culpritsFunctional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetusesAnalysis of chromosome 21 yeast artificial chromosome (YAC) clonesIsolation, characterization, and regional mapping of microclones from a human chromosome 21 microdissection libraryImpaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).A case of apparent trisomy 21 without the Down's syndrome phenotype.Abnormal microRNA expression in Ts65Dn hippocampus and whole blood: contributions to Down syndrome phenotypes.Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21Familial 4.3 Mb duplication of 21q22 sheds new light on the Down syndrome critical regionALK2 mutation in a patient with Down's syndrome and a congenital heart defect.Global differential expression of genes located in the Down Syndrome Critical Region in normal human brain.Down syndrome: molecular mapping of the congenital heart disease and duodenal stenosis.A large, dominant pedigree of atrioventricular septal defect (AVSD): exclusion from the Down syndrome critical region on chromosome 21.Clinical and molecular evaluation of four patients with partial duplications of the long arm of chromosome 18No significant effect of monosomy for distal 21q22.3 on the Down syndrome phenotype in "mirror" duplications of chromosome 21.Protocols to establish genotype-phenotype correlations in Down syndromeDown syndrome phenotypes: the consequences of chromosomal imbalance.Transcriptomic analysis of cell-free fetal RNA suggests a specific molecular phenotype in trisomy 18.Trisomic and allelic differences influence phenotypic variability during development of Down syndrome mice.Molecular mapping of 21 features associated with partial monosomy 21: involvement of the APP-SOD1 regionThe use of mouse models for understanding the biology of down syndrome and agingAntioxidants in Down syndrome.Down syndrome individuals with Alzheimer's disease have a distinct neuroinflammatory phenotype compared to sporadic Alzheimer's disease.The cognitive phenotype of Down syndrome: insights from intracellular network analysisIncreased dosage of DYRK1A and DSCR1 delays neuronal differentiation in neocortical progenitor cells.Gelsolin levels are increased in the brain as a function of age during normal development in children that are further increased in Down syndrome.Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficitsLocalization of a gene for progressive myoclonus epilepsy to chromosome 21q22New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down SyndromeUnraveling the complexity of neurodegeneration in brains of subjects with Down syndrome: insights from proteomics.Systems biological approach to investigate the lack of familial link between Down's Syndrome & Neural Tube Disorders.Mechanisms of ring chromosome formation in 11 cases of human ring chromosome 21.Genome-wide gene expression analysis in the placenta from fetus with trisomy 21.Epigenetic dysregulation in the developing Down syndrome cortex.Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP.Widespread domain-like perturbations of DNA methylation in whole blood of Down syndrome neonates.Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control.
P2860
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P2860
Molecular definition of a region of chromosome 21 that causes features of the Down syndrome phenotype
description
1990 nî lūn-bûn
@nan
1990 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Molecular definition of a regi ...... of the Down syndrome phenotype
@ast
Molecular definition of a regi ...... of the Down syndrome phenotype
@en
Molecular definition of a regi ...... of the Down syndrome phenotype
@en-gb
Molecular definition of a regi ...... of the Down syndrome phenotype
@nl
type
label
Molecular definition of a regi ...... of the Down syndrome phenotype
@ast
Molecular definition of a regi ...... of the Down syndrome phenotype
@en
Molecular definition of a regi ...... of the Down syndrome phenotype
@en-gb
Molecular definition of a regi ...... of the Down syndrome phenotype
@nl
prefLabel
Molecular definition of a regi ...... of the Down syndrome phenotype
@ast
Molecular definition of a regi ...... of the Down syndrome phenotype
@en
Molecular definition of a regi ...... of the Down syndrome phenotype
@en-gb
Molecular definition of a regi ...... of the Down syndrome phenotype
@nl
P2093
P2860
P1476
Molecular definition of a regi ...... of the Down syndrome phenotype
@en
P2093
H Kawashima
J R Korenberg
K Yamamoto
N Ogasawara
S A Schonberg
P2860
P304
P407
P577
1990-08-01T00:00:00Z