Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).
about
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down SyndromeEffects of neonatal neural progenitor cell implantation on adult neuroanatomy and cognition in the Ts65Dn model of Down syndromeA chemical with proven clinical safety rescues Down-syndrome-related phenotypes in through DYRK1A inhibitionPrioritizing the development of mouse models for childhood brain disordersAmygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD.Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.The effect of PN-1, a Traditional Chinese Prescription, on the Learning and Memory in a Transgenic Mouse Model of Alzheimer's Disease.NBM-T-L-BMX-OS01, Semisynthesized from Osthole, Is a Novel Inhibitor of Histone Deacetylase and Enhances Learning and Memory in RatsCD38 facilitates recovery from traumatic brain injuryBehavioral characterization of a mouse model overexpressing DSCR1/ RCAN1.Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndromeActivity-dependent facilitation of Synaptojanin and synaptic vesicle recycling by the Minibrain kinaseEnvironmental enrichment enhances episodic-like memory in association with a modified neuronal activation profile in adult mice.Harmine treatment enhances short-term memory in old rats: Dissociation of cognition and the ability to perform the procedural requirements of maze testing.Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition.Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.Combined Treatment With Environmental Enrichment and (-)-Epigallocatechin-3-Gallate Ameliorates Learning Deficits and Hippocampal Alterations in a Mouse Model of Down Syndrome.Efficient and rapid generation of large genomic variants in rats and mice using CRISMEREThe formation and stability of recognition memory: what happens upon recall?Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?Functional implications of hippocampal adult neurogenesis in intellectual disabilities.Effective expression of Drebrin in hippocampus improves cognitive function and alleviates lesions of Alzheimer's disease in APP (swe)/PS1 (ΔE9) mice.DYRK1A inhibition as potential treatment for Alzheimer's disease.Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism.Dietary teasaponin ameliorates alteration of gut microbiota and cognitive decline in diet-induced obese miceObject recognition test in mice.Rigor and Reproducibility in Rodent Behavioral Research.Curcuma treatment prevents cognitive deficit and alteration of neuronal morphology in the limbic system of aging rats.Strain-independent global effect of hippocampal proteins in mice trained in the Morris water maze.Valproate improves memory deficits in an Alzheimer's disease mouse model: investigation of possible mechanisms of action.Teasaponin improves leptin sensitivity in the prefrontal cortex of obese mice.Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly.Dyrk1a regulates the cardiomyocyte cell cycle via D-cyclin-dependent Rb/E2f-signalling.
P2860
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P2860
Impaired spatial learning strategies and novel object recognition in mice haploinsufficient for the dual specificity tyrosine-regulated kinase-1A (Dyrk1A).
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@ast
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@en
type
label
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@ast
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@en
prefLabel
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@ast
Impaired spatial learning stra ...... -regulated kinase-1A (Dyrk1A).
@en
P2860
P50
P1433
P1476
Impaired spatial learning stra ...... e-regulated kinase-1A (Dyrk1A)
@en
P2093
David Fernández
Vassiliki Fotaki
P2860
P356
10.1371/JOURNAL.PONE.0002575
P407
P577
2008-07-02T00:00:00Z