Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies.
about
mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availabilityEarly Programming by Protein Intake: The Effect of Protein on Adiposity Development and the Growth and Functionality of Vital OrgansExcessive Leucine-mTORC1-Signalling of Cow Milk-Based Infant Formula: The Missing Link to Understand Early Childhood ObesityGender-specific metabolomic profiling of obesity in leptin-deficient ob/ob mice by 1H NMR spectroscopyThe brain's response to an essential amino acid-deficient diet and the circuitous route to a better mealLeucine signaling in the pathogenesis of type 2 diabetes and obesityNovel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling.The general amino acid control pathway regulates mTOR and autophagy during serum/glutamine starvationControl of translation initiation through integration of signals generated by hormones, nutrients, and exerciseThe immunosuppressant rapamycin mimics a starvation-like signal distinct from amino acid and glucose deprivation.Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways.Amino acid transporters: roles in amino acid sensing and signalling in animal cells.miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM PathwaysAssociation of branched and aromatic amino acids levels with metabolic syndrome and impaired fasting glucose in hypertensive patients.Metabolic stress in autophagy and cell death pathwaysProline dehydrogenase is essential for proline protection against hydrogen peroxide-induced cell deathThe impact of cow's milk-mediated mTORC1-signaling in the initiation and progression of prostate cancerTherapeutic interventions to disrupt the protein synthetic machinery in melanomaMutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia.The effects of phosphatidic acid supplementation on strength, body composition, muscular endurance, power, agility, and vertical jump in resistance trained men.PRLR regulates hepatic insulin sensitivity in mice via STAT5.Amino acid regulation of TOR complex 1.Direct Sensing of Nutrients via a LAT1-like Transporter in Drosophila Insulin-Producing Cells.Inability to replete white adipose tissue during recovery phase of sepsis is associated with increased autophagy, apoptosis, and proteasome activity.Regulation of metabolic health and aging by nutrient-sensitive signaling pathways.Decreased Whole-Body Fat Mass Produced by Chronic Alcohol Consumption is Associated with Activation of S6K1-Mediated Protein Synthesis and Increased Autophagy in Epididymal White Adipose Tissue.Leucine and alpha-ketoisocaproic acid, but not norleucine, stimulate skeletal muscle protein synthesis in neonatal pigs.Protective effect of branched chain amino acids on hindlimb suspension-induced muscle atrophy in growing rats.Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.Upstream signalling of mTORC1 and its hyperactivation in type 2 diabetes (T2D).Evidence for Pipecolate Oxidase in Mediating Protection Against Hydrogen Peroxide Stress.Abemaciclib, a Selective CDK4/6 Inhibitor Enhances the Radiosensitivity of Non-Small Cell Lung Cancer in vitro and in vivo.Microbiome-metabolome signatures in mice genetically prone to develop dementia, fed a normal or fatty diet.
P2860
Q24607244-25BC4069-9DE4-483D-A92D-D388016F40B6Q28087534-BC7248E5-C23F-4DD9-91D2-4751ED83D5CAQ28265085-7DCA5D55-15CB-4299-AC94-B82EB220C889Q28534040-8916918B-4A78-4190-832A-7E511D1D608AQ28727183-9F5080E7-FDDB-43B0-87BE-1AB09A4EB7E7Q29543116-7885AA48-A0A5-4CBE-B079-5E50BCF82135Q30532837-6D933905-3D4D-40AB-AA20-6FB861558A9BQ33937744-CD9E5C0A-2B72-40CB-9E93-B31E40B04794Q34121427-949B7DAB-AFBA-4BF4-A556-3C7780CEA23EQ34283579-8984DA97-1B56-4E74-A4E6-8D764624F532Q34615384-E4774BCC-7F02-4ED7-9548-E106EDFC3DBEQ35184476-B284D71C-AF61-4A8F-93B8-9B8960EC366AQ35676981-40026ED2-0CF6-4D56-B385-2C6D3531E14FQ35900537-F08DAB81-BD9E-45D7-A71D-28CCCC7FAB1CQ36192905-A918C820-A5A4-41F3-A405-B6D92AA0B067Q36203215-1904CA1A-1CF7-4F3E-9E0C-07C6727DCF2BQ36402333-64E0E293-B643-4071-A98D-DFC46429B93AQ36473355-A4CAED67-5B66-4FD2-9BE4-DE9FB68A69E5Q36803093-65166656-1892-49A1-86BF-702DA08BCB52Q36965746-0F7D66CF-2215-47CE-9274-B10845C35573Q37110571-D185ED39-785A-4626-8630-D6503764C2A1Q37162253-77C15982-EC48-4590-A012-B6476BA71A20Q37321687-3B8884D7-4FB3-405D-85E7-D913D6198A13Q39013918-019673FC-8272-4EAA-AA8C-F0A729822102Q39019128-1F78A53C-715C-4220-9DD8-3B85D3B57BF6Q41001125-0BCFE558-005D-4BFF-A3F0-A2222B0438D8Q41761908-68E2AB1A-1207-4F88-9577-AE3B8C6CD5DFQ41954738-855E4280-EE92-407C-9546-EE6A752CA6EEQ42818693-8B87B92A-4519-4F7B-B9AA-F53FB43F1D67Q49413554-692170F4-5BA0-4059-A90A-B22FAA1B9396Q51283525-B4004860-7C4C-43AC-A036-1B7E27E0F300Q52714962-C4775564-EF00-4C90-8D02-E0106AC2419AQ55192874-F36104F5-07EC-4E01-9052-D8DA720217CC
P2860
Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Role of leucine in the regulat ...... om structure-activity studies.
@ast
Role of leucine in the regulat ...... om structure-activity studies.
@en
Role of leucine in the regulat ...... om structure-activity studies.
@nl
type
label
Role of leucine in the regulat ...... om structure-activity studies.
@ast
Role of leucine in the regulat ...... om structure-activity studies.
@en
Role of leucine in the regulat ...... om structure-activity studies.
@nl
prefLabel
Role of leucine in the regulat ...... om structure-activity studies.
@ast
Role of leucine in the regulat ...... om structure-activity studies.
@en
Role of leucine in the regulat ...... om structure-activity studies.
@nl
P356
P1433
P1476
Role of leucine in the regulat ...... om structure-activity studies.
@en
P2093
P304
P356
10.1093/JN/131.3.861S
P407
P577
2001-03-01T00:00:00Z