Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
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New Molecular Insights of Insulin in Diabetic CardiomyopathyProtein quality control and metabolism: bidirectional control in the heartImbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in miceMitochondrial dysfunction in cardiac agingInsulin Signaling and Heart Failure.Maintaining PGC-1α expression following pressure overload-induced cardiac hypertrophy preserves angiogenesis but not contractile or mitochondrial function.Insulin inhibits cardiac contractility by inducing a Gi-biased β2-adrenergic signaling in hearts.Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.Metabolic control of autophagyLipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activityUnbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathyInduction of autophagy markers is associated with attenuation of miR-133a in diabetic heart failure patients undergoing mechanical unloading.Antioxidant treatment normalizes mitochondrial energetics and myocardial insulin sensitivity independently of changes in systemic metabolic homeostasis in a mouse model of the metabolic syndrome.Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection.Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy.Exercise training improves vascular mitochondrial function.Cardiomyocyte health: adapting to metabolic changes through autophagy.Molecular mechanisms of diabetic cardiomyopathy.Insulin regulation of myocardial autophagy.Autophagy in cardiac metabolic control: Novel mechanisms for cardiovascular disorders.Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential.DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress.Diabetic cardiomyopathy: a clinical entity or a cluster of molecular heart changes?Myocardial stress and autophagy: mechanisms and potential therapies.FTY720 (Gilenya) treatment prevents spontaneous autoimmune myocarditis and dilated cardiomyopathy in transgenic HLA-DQ8-BALB/c mice.Partial deletion of ROCK2 protects mice from high-fat diet-induced cardiac insulin resistance and contractile dysfunction.p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation.Metabolic Origins of Heart Failure.Mitophagy as a Protective Mechanism against Myocardial Stress.Insulin-Like Growth Factor 1 in the Cardiovascular System.The spectrum of myocardial homeostasis mechanisms in the settings of cardiac surgery procedures (Review).Glucose transporter 4-deficient hearts develop maladaptive hypertrophy in response to physiological or pathological stresses.Activation of IGF-1 receptors and Akt signaling by systemic hyperinsulinemia contributes to cardiac hypertrophy but does not regulate cardiac autophagy in obese diabetic mice.Macroautophagy and Chaperone-Mediated Autophagy in Heart Failure: The Known and the Unknown.Molecular mechanism of diabetic cardiomyopathy and modulation of microRNA function by synthetic oligonucleotides.
P2860
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P2860
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@en
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@nl
type
label
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@en
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@nl
prefLabel
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@en
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.
@nl
P2093
P2860
P50
P356
P1476
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart
@en
P2093
Adam R Wende
Christian Riehle
Cynthia N Perry
Deborah Frank
Jack Bevins
Karla Maria Pires
Monika Rech
Morris F White
Renata Oliveira Pereira
P2860
P304
P356
10.1172/JCI71171
P407
P577
2013-11-01T00:00:00Z