Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
about
Thrombin inhibits tumor cell growth in association with up-regulation of p21(waf/cip1) and caspases via a p53-independent, STAT-1-dependent pathwayHigh-affinity self-reactive human antibodies by design and selection: targeting the integrin ligand binding siteDeadly allies: the fatal interplay between platelets and metastasizing cancer cellsOvarian cancer, the coagulation pathway, and inflammationInteraction between circulating cancer cells and platelets: clinical implicationThe platelet aggregation-inducing factor aggrus/podoplanin promotes pulmonary metastasisHuman cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions.NF-E2 p45 is important for establishing normal function of platelets.Actions of heparin that may affect the malignant process.Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration.Characterization of the MDSC proteome associated with metastatic murine mammary tumors using label-free mass spectrometry and shotgun proteomicsP-selectin mediates adhesion of platelets to neuroblastoma and small cell lung cancerLigand bridging mediates integrin alpha IIb beta 3 (platelet GPIIB-IIIA) dependent homotypic and heterotypic cell-cell interactions.Integrins and bone metastasis: integrating tumor cell and stromal cell interactions.Correlation analysis connects cancer subtypes.Plasma von Willebrand factor level as a prognostic indicator of patients with metastatic colorectal carcinomaFactor X inhibitors.Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrateFibrin serves as a divalent ligand that regulates neutrophil-mediated melanoma cells adhesion to endothelium under shear conditionsThrombospondin modulates melanoma--platelet interactions and melanoma tumour cell growth in vivo.Tissue factor activity of SW-480 human colon adenocarcinoma cells is modulated by thrombin and protein kinase C activation.Protease-activated receptors in cancer: A systematic review.Protease-activated receptors (PARs)--biology and role in cancer invasion and metastasis.Persistent signaling by dysregulated thrombin receptor trafficking promotes breast carcinoma cell invasionThe initial hours of metastasis: the importance of cooperative host-tumor cell interactions during hematogenous disseminationConcentration dependent dual effect of thrombin in endothelial cells via Par-1 and Pi3 Kinase.Thrombin induces tumor cell cycle activation and spontaneous growth by down-regulation of p27Kip1, in association with the up-regulation of Skp2 and MiR-222Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement.A randomized phase II trial investigating the effect of platelet function inhibition on circulating tumor cells in patients with metastatic breast cancerPlatelets: linking hemostasis and cancer.Platelet-targeted pharmacologic treatments as anti-cancer therapy.Circulating and disseminated tumor cells: harbingers or initiators of metastasis?Thrombin-unique coagulation system protein with multifaceted impacts on cancer and metastasis.The clinical value of von Willebrand factor in colorectal carcinomas.Proinflammatory signaling functions of thrombin in cancer.Concentration dependent anti-inflammatory effects thrombin on polyphosphate-mediated inflammatory responses in vitro and in vivo.Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia.Platelets as crucial partners for tumor metastasis: from mechanistic aspects to pharmacological targeting.Procoagulant properties of human MV3 melanoma cells.Elevated preoperative plasma D-dimer level is a useful predictor of chemoresistance and poor disease outcome for serous ovarian cancer patients.
P2860
Q22253244-EFA5F83F-A680-41BB-B94F-9F61783521D7Q24564554-6D1DB6D8-DAE4-401D-BE9A-516F184DB4EEQ24623647-0F4F3E1E-3A11-4A50-A4C0-FC1EDB21A40BQ24816796-7A18C76C-8D49-41A3-B710-8A93D6819B58Q26778920-C8EE8041-9F76-4830-BBA4-9EB5E1945542Q28221740-3A16737F-6A15-4B31-A70E-152A4FB3C644Q32021129-00CA7A8D-5462-4973-9961-06772E9E2B81Q33407515-6F01F681-19E8-470D-8322-DFDD03DFA3C5Q33534337-9AB0FE8C-82DB-4E54-85BE-6EEB254BE665Q33723243-5FE4F107-AE1E-44D5-87B4-9EB77225B6B8Q33996767-5DE76792-52A2-4F53-A4EE-66BB8C11CCBBQ34171030-28BD4AC4-E177-489E-AE40-5F1910F64C2DQ34203181-A117127D-67A9-4D7E-8B78-8E1AD2C54754Q34441622-8BA200E7-64EA-4B29-B142-F3E344838C71Q34828696-AC16DB79-AD43-4CD1-B264-9D8CFADB3418Q35010760-A3383435-4F7C-4307-99D6-30C31ACCFEE8Q35117073-FF4EA25A-0A5D-447C-8C85-C8B1355A8275Q35873003-3914974B-6CAF-45DB-A643-44B094FC300DQ35900663-BEB75CDF-EA9E-4937-A59D-052847B5F555Q36081857-0E5798B2-5E63-4EE3-8D7B-95349D6341CCQ36115096-3F620125-B065-4D0B-A55A-972B031E73D8Q36121203-6DF584CC-4966-4BB6-A1AA-022226D89EA2Q36322931-42368A9F-8D15-47FB-AC3B-D369AAF0022FQ36420521-EE6F4903-5B78-4F02-B31D-F1678CE075D9Q36520882-B102D7B4-DC07-4DD1-8C2E-0B90D90B4D32Q37146006-1CE9E45A-F5B2-466C-A6C1-3D5D11884180Q37188430-4397CC6B-FF2A-4146-8BF5-3F3212DFEA2FQ37334647-A98DAEE6-9D9F-4DBD-AD65-6D5E25E76243Q37630295-002774B5-59D7-4745-85A7-FB1894E44C80Q37808901-AC82C66C-F336-4C06-BA2F-D0CA0AE157D0Q38657846-702D2020-4555-4A6E-B385-23E67668F3DCQ38770774-3388695F-C563-47B3-ADF8-D02B36A5BAB1Q38836736-974E9D62-456B-41C8-9E3E-47BFED8D8207Q38880592-03A2E9BB-010F-4228-886C-8C0F2CA7A542Q39048394-44C6840C-D933-4BE1-87F2-82C1B278095EQ39178318-0E71C8BE-8682-478F-8C46-D90B71E6C98CQ39209792-FEBDB597-7725-45D9-91E5-1C4FB7091FADQ39294808-7D5B8900-A97B-4704-A2A4-5FF68B5B6646Q40018577-CE46A66F-3060-4273-BDE7-D71CF366B031Q40350703-61C2EDDF-4C4F-43D6-8E24-63B0064E4D0F
P2860
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@ast
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@en
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@nl
type
label
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@ast
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@en
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@nl
prefLabel
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@ast
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@en
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@nl
P2093
P2860
P356
P1476
Thrombin stimulates tumor-platelet adhesion in vitro and metastasis in vivo.
@en
P2093
M L Nierodzik
S Karpatkin
P2860
P304
P356
10.1172/JCI114976
P407
P577
1991-01-01T00:00:00Z