FRET detection of cellular alpha4-integrin conformational activation.
about
Disruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsMechanical regulation of T-cell functionsTransition metal ion FRET to measure short-range distances at the intracellular surface of the plasma membrane.Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3ɛ Cytoplasmic Tyrosine-Based MotifCrystal structure of the complete integrin αVβ3 ectodomain plus an α/β transmembrane fragmentFluorescence applications in molecular neurobiologyFocal adhesions are sites of integrin extension.Equilibrium and kinetics of Sin Nombre hantavirus binding at DAF/CD55 functionalized bead surfaces.Catch-bond model derived from allostery explains force-activated bacterial adhesion.Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography.Interlaced optical force-fluorescence measurements for single molecule biophysics.Allosteric modulation of beta1 integrin function induces lung tissue repairObserving force-regulated conformational changes and ligand dissociation from a single integrin on cells.Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.Outside-in signal transmission by conformational changes in integrin Mac-1Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.Regulation of catch binding by allosteric transitions.Human epidermal growth factor receptor (HER1) aligned on the plasma membrane adopts key features of Drosophila EGFR asymmetry.Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stressElongated membrane tethers, individually anchored by high affinity α4β1/VCAM-1 complexes, are the quantal units of monocyte arrests.FRET detection of lymphocyte function-associated antigen-1 conformational extension.Why integrin as a primary target for imaging and therapy.Conformational mAb as a tool for integrin ligand discoveryReal-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.Elevated cytokines, thrombin and PAI-1 in severe HCPS patients due to Sin Nombre virus.Quantifying the relation between adhesion ligand-receptor bond formation and cell phenotype.Reconstruction of integrin activation.The interaction with H-2D(d) in cis is associated with a conformational change in the Ly49A NK cell receptor.Synapses: sites of cell recognition, adhesion, and functional specification.The Structure of a Full-length Membrane-embedded Integrin Bound to a Physiological LigandMoving toward the light: using new technology to answer old questionsIntegrin structures and conformational signalingFluorescent resonance energy transfer: A tool for probing molecular cell-biomaterial interactions in three dimensionsStructure and mechanics of integrin-based cell adhesion.Osteopontin binding to the alpha 4 integrin requires highest affinity integrin conformation, but is independent of post-translational modifications of osteopontin.Visualizing and quantifying adhesive signals.Demonstration of catch bonds between an integrin and its ligand.Catch-bond mechanism of force-enhanced adhesion: counterintuitive, elusive, but ... widespread?Rapid parallel flow cytometry assays of active GTPases using effector beads.
P2860
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P2860
FRET detection of cellular alpha4-integrin conformational activation.
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
FRET detection of cellular alpha4-integrin conformational activation.
@ast
FRET detection of cellular alpha4-integrin conformational activation.
@en
FRET detection of cellular alpha4-integrin conformational activation.
@nl
type
label
FRET detection of cellular alpha4-integrin conformational activation.
@ast
FRET detection of cellular alpha4-integrin conformational activation.
@en
FRET detection of cellular alpha4-integrin conformational activation.
@nl
prefLabel
FRET detection of cellular alpha4-integrin conformational activation.
@ast
FRET detection of cellular alpha4-integrin conformational activation.
@en
FRET detection of cellular alpha4-integrin conformational activation.
@nl
P2093
P2860
P1433
P1476
FRET detection of cellular alpha4-integrin conformational activation
@en
P2093
Denise C Dwyer
Larry A Sklar
Tione Buranda
P2860
P304
P356
10.1016/S0006-3495(03)74809-7
P407
P577
2003-12-01T00:00:00Z