An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.
about
The zinc finger domain of Wilms' tumor 1 suppressor gene (WT1) behaves as a dominant negative, leading to abrogation of WT1 oncogenic potential in breast cancer cellsTranscription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome3' deletions cause aniridia by preventing PAX6 gene expressionInhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70PAX 8 regulates human WT1 transcription through a novel DNA binding siteCharacterization of the human forkhead gene FREAC-4. Evidence for regulation by Wilms' tumor suppressor gene (WT-1) and p53WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosisClone pAT 133 identifies a gene that encodes another human member of a class of growth factor-induced genes with almost identical zinc-finger domainsHigh affinity binding sites for the Wilms' tumour suppressor protein WT1Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation propertiesWNT5A is regulated by PAX2 and may be involved in blastemal predominant Wilms tumorigenesisClustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cellsRepression of transcriptional activity by heterologous KRAB domains present in zinc finger proteinsIsolation and characterization of a novel zinc-finger protein with transcription repressor activityHuman platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1CITED1 expression in Wilms' tumor and embryonic kidneyZinc finger point mutations within the WT1 gene in Wilms tumor patientsIsolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney developmentWilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNAZebrafish sex determination and differentiation: involvement of FTZ-F1 genesActive specific immunotherapy targeting the Wilms' tumor protein 1 (WT1) for patients with hematological malignancies and solid tumors: lessons from early clinical trialsMammalian sex determination—insights from humans and mice.Wilms' tumor 1 gene mutations independently predict poor outcome in adults with cytogenetically normal acute myeloid leukemia: a cancer and leukemia group B studyThe Denys-Drash syndromeThe many facets of the Wilms' tumour gene, WT1Deletion of IRF-1, mapping to chromosome 5q31.1, in human leukemia and preleukemic myelodysplasiaThe pleural mesothelium in development and diseasePleural mesothelial cells in pleural and lung diseasesPhysical and functional interaction between WT1 and p53 proteinsIn silico regulatory analysis for exploring human disease progression.Mendelian cytogenetics. Chromosome rearrangements associated with mendelian disordersMolecular mechanisms of cancer.Tumor-suppressor genes: cardinal factors in inherited predisposition to human cancersThe Wilms' tumor gene product (WT1) modulates the response to 1,25-dihydroxyvitamin D3 by induction of the vitamin D receptor.A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice.Mutational screening of the Wilms's tumour gene, WT1, in males with genital abnormalities.A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells.Truncated WT1 mutants alter the subnuclear localization of the wild-type protein.Mosaic uniparental disomy in Beckwith-Wiedemann syndrome.Epigenetic modification and uniparental inheritance of H19 in Beckwith-Wiedemann syndrome.
P2860
Q21195233-026A5C4A-F701-44D3-B505-423DD9476197Q22010499-EE65F7D3-77B0-4081-9B3E-3D20910613AAQ24290547-93B69B4C-929D-402B-8164-673B674BC939Q24308507-713AC436-D8BA-47A5-B6BC-8AB03F3569AAQ24310556-E84E4856-F13C-439F-B846-283B49455D36Q24312036-6BDBB15A-506B-4349-AB7C-44FFC91C41E4Q24313596-5DBD3C2A-0794-468C-867C-179732BCE219Q24313627-CD792260-C92F-4D25-87C7-F3F6BBBF2C1AQ24314245-2BEE73F8-DDDB-4AF2-9B05-B5CF2E17DB46Q24318806-442C5E1C-6117-458F-9130-8FD336BA6508Q24320196-DCE51AB8-9BCB-40BE-BCA9-E31015E16589Q24324140-61AFEAD6-E9DB-4F96-95FA-5CF022E9B4A3Q24324594-05E886F3-7895-4991-BFD7-0D0DEC183DAFQ24337444-DEE35641-C16B-45DA-8B5E-723D93D4B451Q24337538-8B7FB140-FB08-454C-8BCF-B39BDC17B86FQ24337902-8E005639-C664-443B-A288-989444B20E87Q24561664-395EC0D5-55FA-4050-BC4C-69E026A84C23Q24607161-0BCB267F-586D-4623-8CD1-2E98A8D11F31Q24675575-16F4DA18-6514-4039-8F7F-8C94E20AE9DFQ24814402-5C1A02EB-A3E3-4879-8A85-EC2DB52252EAQ27026836-350533C5-6FAC-40F5-8A23-75A38F82F8E2Q27691819-4831CDA7-CEFD-4234-BCE5-4F6582B82B7FQ27851436-2353B5BF-CA3A-4A29-A347-D24AFE9095EAQ28247154-D0DCAA8D-FB10-4D1B-BA80-5BB8C737915BQ28264516-6DCB4D8F-6009-4086-9942-9554B14796EAQ28266438-A05E4444-EB6A-469F-A01B-5EE617D66701Q28391520-650A817A-774D-46D2-80AB-D4CC0E7B3FDFQ28396403-D16E0F43-BFBE-4204-B3B8-F76734D7F752Q28575245-53ADA9B2-8B9A-4D3C-BCA8-0B6FD58D03A0Q30482686-093E2534-C879-475A-8B2B-608A6AE7626FQ30495385-06AB4639-DC93-4102-8161-DF96151D64DCQ30498610-7C29E13F-6852-4650-8584-285FA2D48A3BQ30499489-16670C85-7B72-4C16-B5A4-FB48AC916183Q31492470-7B7384D4-5F23-4DB5-8C59-83B0BA5C5958Q33556956-04C32C88-4B91-4D3A-A0C8-C93CD9796BB7Q33595792-B094D473-B8DD-4ADB-80BD-929B4FADA156Q33612442-0489E829-0A12-4EFB-814C-86D42C73C8A7Q33635997-DC5D1C23-9C04-4646-8EF4-348B9C446DA1Q33675226-BB4844B4-E1BC-49DD-94AE-997982006A9DQ33678779-8740552A-4B7D-4870-93DB-B176A5913915
P2860
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor.
description
1990 nî lūn-bûn
@nan
1990 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
An internal deletion within an ...... e development of Wilms' tumor.
@ast
An internal deletion within an ...... e development of Wilms' tumor.
@en
An internal deletion within an ...... e development of Wilms' tumor.
@nl
type
label
An internal deletion within an ...... e development of Wilms' tumor.
@ast
An internal deletion within an ...... e development of Wilms' tumor.
@en
An internal deletion within an ...... e development of Wilms' tumor.
@nl
prefLabel
An internal deletion within an ...... e development of Wilms' tumor.
@ast
An internal deletion within an ...... e development of Wilms' tumor.
@en
An internal deletion within an ...... e development of Wilms' tumor.
@nl
P2093
P1433
P1476
An internal deletion within an ...... e development of Wilms' tumor.
@en
P2093
A J Buckler
D E Housman
E C Douglass
J Pelletier
P304
P356
10.1016/0092-8674(90)90690-G
P407
P577
1990-06-01T00:00:00Z