An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1 - Wikidata - awgldk - TriplyDB

An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1

An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1

http://www.wikidata.org/entity/Q34190199

about

Antisense oligonucleotides: treating neurodegeneration at the level of RNA Alternative translation initiation augments the human mitochondrial proteome Ribonuclease H1-dependent hepatotoxicity caused by locked nucleic acid-modified gapmer antisense oligonucleotides Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response.Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria Targeting nuclear RNA for in vivo correction of myotonic dystrophy RNASEH1 Mutations Impair mtDNA Replication and Cause Adult-Onset Mitochondrial Encephalomyopathy Screen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthase A cryptic targeting signal creates a mitochondrial FEN1 isoform with tailed R-Loop binding properties.REXO2 is an oligoribonuclease active in human mitochondria.Regulation of translation by upstream translation initiation codons of surfactant protein A1 splice variants.Reduction of hRNase H2 activity in Aicardi-Goutières syndrome cells leads to replication stress and genome instability Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome.The interface of transcription and DNA replication in the mitochondria In silico and in vitro evaluation of exonic and intronic off-target effects form a critical element of therapeutic ASO gapmer optimization.Functions of Replication Protein A as a Sensor of R Loops and a Regulator of RNaseH1 Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.Antisense oligonucleotides: rising stars in eliminating RNA toxicity in myotonic dystrophy.Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.The proteome under translational control.Human Ribonuclease H1 resolves R loops and thereby enables progression of the DNA replication fork.Managing the sequence-specificity of antisense oligonucleotides in drug discovery.Myotonic dystrophy: approach to therapy.Human mitochondrial nucleases.R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching.Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames.Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA Dmpk gene deletion or antisense knockdown does not compromise cardiac or skeletal muscle function in mice Translation efficiency of mRNAs is increased by antisense oligonucleotides targeting upstream open reading frames.Antisense oligonucleotides targeting translation inhibitory elements in 5' UTRs can selectively increase protein levels.Dynamic nucleoplasmic and nucleolar localization of mammalian RNase H1 in response to RNAP I transcriptional R-loops.Spliceosomal components protect embryonic neurons from R-loop-mediated DNA damage and apoptosis.RNase H1-Dependent Antisense Oligonucleotides Are Robustly Active in Directing RNA Cleavage in Both the Cytoplasm and the Nucleus.Human copper chaperone for superoxide dismutase 1 mediates its own oxidation-dependent import into mitochondria.

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P2860

An upstream open reading frame and the context of the two AUG codons affect the abundance of mitochondrial and nuclear RNase H1

http://www.wikidata.org/entity/Q34190199

description

2010 nî lūn-bûn

@nan

2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

An upstream open reading frame ...... chondrial and nuclear RNase H1

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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type

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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prefLabel

An upstream open reading frame ...... chondrial and nuclear RNase H1

@ast

An upstream open reading frame ...... chondrial and nuclear RNase H1

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An upstream open reading frame ...... chondrial and nuclear RNase H1

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Molecular and Cellular Biology

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An upstream open reading frame ...... chondrial and nuclear RNase H1

@en

P2093

J Bradley Holmes

http://www.w3.org/2001/XMLSchema#string

Kiran Sakhuja

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Robert J Crouch

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Susana M Cerritelli

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P2860

Cloning, expression, and mapping of ribonucleases H of human and mouse related to bacterial RNase HI

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

Identification and characterization of mammalian mitochondrial tRNA nucleotidyltransferases

Dual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleus

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans

Eukaryotic RNases H1 act processively by interactions through the duplex RNA-binding domain

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair.

Cytoplasmic and mitochondrial tRNA nucleotidyltransferase activities are derived from the same gene in the yeast Saccharomyces cerevisiae.

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

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5123-5134

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scholarly article

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10.1128/MCB.00619-10

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21

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30

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Michał Mińczuk

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2010-09-07T00:00:00Z

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20823270

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2953059

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