Functional analysis of the protein phosphatase activity of PTEN - Wikidata - awgldk - TriplyDB

Functional analysis of the protein phosphatase activity of PTEN

Functional analysis of the protein phosphatase activity of PTEN

http://www.wikidata.org/entity/Q34194118

about

Neuropathology and animal models of autism: genetic and environmental factors Protein tyrosine phosphatases--from housekeeping enzymes to master regulators of signal transduction Multiple Roles of the Small GTPase Rab7 PtdIns(4,5)P2-mediated cell signaling: emerging principles and PTEN as a paradigm for regulatory mechanism Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders Therapeutic targeting of cancers with loss of PTEN function.A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.PTEN is a protein tyrosine phosphatase for IRS1 PTEN modulates EGFR late endocytic trafficking and degradation by dephosphorylating Rab7.Structural mutation analysis of PTEN and its genotype-phenotype correlations in endometriosis and cancer PTEN knockdown alters dendritic spine/protrusion morphology, not density The protein phosphatase activity of PTEN is essential for regulating neural stem cell differentiation.Differential Requirement for Pten Lipid and Protein Phosphatase Activity during Zebrafish Embryonic Development.Phosphatase and tensin homolog is a differential diagnostic marker between nonalcoholic and alcoholic fatty liver disease.A recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndrome PTEN inhibits PREX2-catalyzed activation of RAC1 to restrain tumor cell invasion.Phosphorylation-mediated PTEN conformational closure and deactivation revealed with protein semisynthesis.Loss of mTOR repressors Tsc1 or Pten has divergent effects on excitatory and inhibitory synaptic transmission in single hippocampal neuron cultures.Role of the PTEN signaling pathway in autism spectrum disorder.PTEN function: the long and the short of it.Plk1 phosphorylation of PTEN causes a tumor-promoting metabolic state.PTEN proteoforms in biology and disease.Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome.Intrinsic disorder in PTEN and its interactome confers structural plasticity and functional versatility.PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer.The GAS5/miR-222 Axis Regulates Proliferation of Gastric Cancer Cells Through the PTEN/Akt/mTOR Pathway.PTEN/PTENP1: 'Regulating the regulator of RTK-dependent PI3K/Akt signalling', new targets for cancer therapy.Endogenous Control Mechanisms of FAK and PYK2 and Their Relevance to Cancer Development.

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P2860

Functional analysis of the protein phosphatase activity of PTEN

http://www.wikidata.org/entity/Q34194118

description

2012 nî lūn-bûn

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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Functional analysis of the protein phosphatase activity of PTEN

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Functional analysis of the protein phosphatase activity of PTEN

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Functional analysis of the protein phosphatase activity of PTEN

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type

label

Functional analysis of the protein phosphatase activity of PTEN

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Functional analysis of the protein phosphatase activity of PTEN

@en

Functional analysis of the protein phosphatase activity of PTEN

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prefLabel

Functional analysis of the protein phosphatase activity of PTEN

@ast

Functional analysis of the protein phosphatase activity of PTEN

@en

Functional analysis of the protein phosphatase activity of PTEN

@nl

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Biochemical Journal

P1476

Functional analysis of the protein phosphatase activity of PTEN

@en

P2093

Antonella Piccini

http://www.w3.org/2001/XMLSchema#string

Linda Van Aelst

http://www.w3.org/2001/XMLSchema#string

Michael P Myers

http://www.w3.org/2001/XMLSchema#string

Nicholas K Tonks

http://www.w3.org/2001/XMLSchema#string

Xiaoqun Catherine Zhang

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P2860

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

Phosphorylation of the PTEN tail regulates protein stability and function

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

Phosphatase and tensin homolog, deleted on chromosome 10 deficiency in brain causes defects in synaptic structure, transmission and plasticity, and myelination abnormalities

Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

Autophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivo

Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

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457-464

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scholarly article

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10.1042/BJ20120098

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3

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444

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2012-06-01T00:00:00Z

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221891737

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22413754

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3365644

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