Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
about
Inhibition of O6-methylguanine-DNA methyltransferase by an alkyltransferase-like protein from Escherichia coli.Atl1 Regulates Choice between Global Genome and Transcription-Coupled Repair of O6-AlkylguaninesSingle nucleotide polymorphisms in DNA repair genes and prostate cancer riskMGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studiesGenome-wide analysis of alternative splicing in Volvox carteriMechanism to trigger unfolding in O(6) -alkylguanine-DNA alkyltransferase.DNA repair and cancer: lessons from mutant mouse models.Variants of DNA repair genes and the risk of biliary tract cancers and stones: a population-based study in China.Expression of O-Alkylguanine-DNA Alkyltransferase in Normal and Malignant Bladder Tissue of Egyptian PatientsMGMT promoter methylation and field defect in sporadic colorectal cancer.The nitrosated bile acid DNA lesion O6-carboxymethylguanine is a substrate for the human DNA repair protein O6-methylguanine-DNA methyltransferase.Alkyltransferase-like proteins: molecular switches between DNA repair pathways.Major differences between tumor and normal human cell fates after exposure to chemotherapeutic monofunctional alkylatorPrognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?Human colorectal mucosal O6-alkylguanine DNA-alkyltransferase activity and DNA-N7-methylguanine levels in colorectal adenoma cases and matched referents.Inhibition of STAT3 reverses drug resistance acquired in temozolomide-resistant human glioma cells.O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenograftsMethylation in esophageal carcinogenesis.S-alkylthiolation of O6-methylguanine-DNA-methyltransferase (MGMT) to sensitize cancer cells to anticancer therapy.DNA alkylation and DNA methylation: cooperating mechanisms driving the formation of colorectal adenomas and adenocarcinomas?Genomic predictors of interindividual differences in response to DNA damaging agentsThe therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors.Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.Alkyltransferase-mediated toxicity of 1,3-butadiene diepoxide.Substitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.Mode of action of the chloroethylating and carbamoylating moieties of the prodrug cloretazine.CpG methylation analysis--current status of clinical assays and potential applications in molecular diagnostics: a report of the Association for Molecular Pathology.Validation of biomarkers for the study of environmental carcinogens: a review.Promoter methylation of tumor suppressor genes in esophageal squamous cell carcinoma.Correlation of histomorphologic prognostic markers and proliferative index with loss of heterozygosity 1p/19q and MGMT status in diffusely infiltrating gliomas.Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein.Breast cancer adaptive resistance: HER2 and cancer stem cell repopulation in a heterogeneous tumor society.Enhanced MGMT expression contributes to temozolomide resistance in glioma stem-like cells.Influence of promoter/enhancer region haplotypes on MGMT transcriptional regulation: a potential biomarker for human sensitivity to alkylating agents.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Aggressive pituitary tumours: the role of temozolomide and the assessment of MGMT status.Pituitary carcinomas and aggressive pituitary tumours: merits and pitfalls of temozolomide treatment.DNA repair by reversal of DNA damage.A novel DNA damage recognition protein in Schizosaccharomyces pombe.The correlation and prognostic significance of MGMT promoter methylation and MGMT protein in glioblastomas.
P2860
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P2860
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@ast
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@en
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@nl
type
label
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@ast
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@en
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@nl
prefLabel
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@ast
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@en
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@nl
P2093
P356
P1433
P1476
Variability and regulation of O6-alkylguanine-DNA alkyltransferase.
@en
P2093
Andrew C Povey
Bernd Kaina
Geoffrey P Margison
Mauro F Santibáñez Koref
P304
P356
10.1093/CARCIN/BGG005
P407
P577
2003-04-01T00:00:00Z