Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.
about
Differential inactivation of polymorphic variants of human O6-alkylguanine-DNA alkyltransferase.Substitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.Enhanced MGMT expression contributes to temozolomide resistance in glioma stem-like cells.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.
P2860
Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 September 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inactivation of O
@nl
Inactivation of O(6)-alkylguan ...... (hydroxymethyl)benzyl]guanine.
@en
type
label
Inactivation of O
@nl
Inactivation of O(6)-alkylguan ...... (hydroxymethyl)benzyl]guanine.
@en
prefLabel
Inactivation of O
@nl
Inactivation of O(6)-alkylguan ...... (hydroxymethyl)benzyl]guanine.
@en
P2093
P2860
P356
P1476
Inactivation of O(6)-alkylguan ...... (hydroxymethyl)benzyl]guanine.
@en
P2093
Anthony E Pegg
Gary T Pauly
Natalia A Loktionova
Qingming Fang
Robert C Moschel
Sahar Javanmard
P2860
P304
P356
10.1021/JM0705859
P407
P577
2007-09-20T00:00:00Z