Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.

Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.

Item
http://www.wikidata.org/entity/Q34198487
Identification of fragments targeting an alternative pocket on HIV-1 gp41 by NMR screening and similarity searching.Design and characterization of swapped-domain constructs of HIV-1 glycoprotein-41 as receptors for drug discovery.Discovery libraries targeting the major enzyme classes: the serine hydrolases.Comprehensive peptidomimetic libraries targeting protein-protein interactions.Enhanced potency of bivalent small molecule gp41 inhibitors.NMR-assisted computational studies of peptidomimetic inhibitors bound in the hydrophobic pocket of HIV-1 glycoprotein 41.State-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.Synthesis of highly functionalized oligobenzamide proteomimetic foldamers by late stage introduction of sensitive groups.Approaches for identification of HIV-1 entry inhibitors targeting gp41 pocketComputer-Aided Approaches for Targeting HIVgp41.Recapitulating the α-helix: nonpeptidic, low-molecular-weight ligands for the modulation of helix-mediated protein-protein interactions.Structure-activity relationship studies of indole-based compounds as small molecule HIV-1 fusion inhibitors targeting glycoprotein 41.Efficient α-helix induction in a linear peptide chain by N-capping with a bridged-tricyclic diproline analogue.Limiting Assumptions in the Design of Peptidomimetics.A modular synthesis of teraryl-based α-helix mimetics, part 1: Synthesis of core fragments with two electronically differentiated leaving groups.
P2860

Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library.

Item
http://www.wikidata.org/entity/Q34198487
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@ast
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@en
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@nl
type
label
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@ast
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@en
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@nl
prefLabel
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@ast
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@en
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P932
P356
P1433
P1476
Discovery of HIV fusion inhibi ...... nsive α-helix mimetic library.
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2012.02.062
P407
P433
P478
P577
P5875
P698
P932