ATX-LPA receptor axis in inflammation and cancer. - Wikidata - awgldk - TriplyDB

ATX-LPA receptor axis in inflammation and cancer.

ATX-LPA receptor axis in inflammation and cancer.

http://www.wikidata.org/entity/Q34199719

about

Recent advances in targeting the autotaxin-lysophosphatidate-lipid phosphate phosphatase axis in vivo A metabolically-stabilized phosphonate analog of lysophosphatidic acid attenuates collagen-induced arthritis SNMIB/Apollo protects leading-strand telomeres against NHEJ-mediated repair A murine preclinical syngeneic transplantation model for breast cancer precision medicine.SPAG5 upregulation predicts poor prognosis in cervical cancer patients and alters sensitivity to taxol treatment via the mTOR signaling pathway.Targeting the hydrophobic pocket of autotaxin with virtual screening of inhibitors identifies a common aromatic sulfonamide structural motif.Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling.Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.DNA damage response and tumorigenesis in Mcm2-deficient mice Lysophosphatidic Acid Upregulates Laminin-332 Expression during A431 Cell Colony Dispersal.Autotaxin-lysophosphatidic acid signaling axis mediates tumorigenesis and development of acquired resistance to sunitinib in renal cell carcinoma.Lysophosphatidic acid enhances vascular endothelial growth factor-C expression in human prostate cancer PC-3 cells.The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.Constitutive autotaxin transcription by Nmyc-amplified and non-amplified neuroblastoma cells is regulated by a novel AP-1 and SP-mediated mechanism and abrogated by curcumin.Chemical genetics screening reveals KIAA1363 as a cytokine-lowering target.Autotaxin downregulates LPS-induced microglia activation and pro-inflammatory cytokines production.A critical role of Gbetagamma in tumorigenesis and metastasis of breast cancer.S100A8/A9 activate key genes and pathways in colon tumor progression.Mitogenic Signaling by the gep Oncogene Involves the Upregulation of S-Phase Kinase-Associated Protein 2.Adipose-specific disruption of autotaxin enhances nutritional fattening and reduces plasma lysophosphatidic acid.Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution The autotaxin-lysophosphatidic acid-lysophosphatidic acid receptor cascade: proposal of a novel potential therapeutic target for treating glioblastoma multiforme A new hypothesis for the cancer mechanism.Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanoma.CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma.Lysophosphatidic acid-induced p21Waf1 expression mediates the cytostatic response of breast and ovarian cancer cells to TGFβ.Autotaxin/ENPP2 regulates oligodendrocyte differentiation in vivo in the developing zebrafish hindbrain.Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression Higher plasma levels of lysophosphatidylcholine 18:0 are related to a lower risk of common cancers in a prospective metabolomics study Homology modeling and docking studies of ENPP4: a BCG activated tumoricidal macrophage protein.Active YAP promotes pancreatic cancer cell motility, invasion and tumorigenesis in a mitotic phosphorylation-dependent manner through LPAR3 TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation.Growth of triple-negative breast cancer cells relies upon coordinate autocrine expression of the proinflammatory cytokines IL-6 and IL-8.Simvastatin suppresses the DNA replication licensing factor MCM7 and inhibits the growth of tamoxifen-resistant breast cancer cells.MCM7 promotes cancer progression through cyclin D1-dependent signaling and serves as a prognostic marker for patients with hepatocellular carcinoma.Simvastatin and Atorvastatin inhibit DNA replication licensing factor MCM7 and effectively suppress RB-deficient tumors growth.Autotaxin inhibitors: a patent review (2012-2016).Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models.Autotaxin and its product lysophosphatidic acid suppress brown adipose differentiation and promote diet-induced obesity in mice.

P2860

Q26741062-DD2344F6-80AF-44F3-8BA4-A68FDD09F686 Q28534911-8B5E3937-40B4-4BD6-9952-1CDF1285A0F2 Q28593511-88C296AF-2FB5-4677-8F4B-FB9ED28160C7 Q33580224-11C291F9-D89A-452F-9C18-5048A970AFB4 Q33720115-B6697ACD-9F3A-4B7A-B61F-77C3358DF7E9 Q33723239-3095AF32-4763-4F5A-BF87-2391BD290E85 Q33781318-41F0D7C0-E62B-4EE4-809A-535D666023F7 Q33786774-EAA23328-E0A8-4010-94AA-E62E65F1E3E9 Q33846709-0DE8E9E8-5EA9-4A06-AE6C-56DB94DB0F23 Q33940639-A5AF6551-A902-42CB-9378-DF38C98E4D7C Q34123656-43C564C0-5FEB-4170-A82D-12F1E443579B Q34314916-E6FF10C3-9ABA-42DE-AFEC-5432164EDF9F Q34387665-925349AB-EE1B-4051-8C58-164F7CDF5BBD Q34474291-6CC0AF33-C2FA-4EFD-9C10-9C1FBF8C395A Q34642602-7A00F474-9276-44E4-8B37-5BB4D2B7FF4B Q34756802-917C9347-07D6-4D59-A2B4-F363395A2B24 Q34764899-143E3D28-8F53-44E6-808F-9576FACEA8C5 Q34787134-75B7F6B9-1057-419A-8E6D-3E7FDCC3BF91 Q34802977-BF9D9CCF-FF90-4993-BE23-6B51811DACE7 Q34866982-24355BC7-F8CC-46AF-8CF7-AB02CF6B706E Q34956002-45E86D8C-440F-4DCB-B4E0-4A11BF4C9FF8 Q35314358-0B003D44-8027-4FFF-959E-3810D7EF4E64 Q35770218-E0B04CEA-DBCB-4B6A-8592-7989E9266172 Q35954093-5873F1D3-0D77-4929-9B1F-362CF6428C3A Q36011319-0A5B26F0-B6DB-4EDA-89E0-D74BD329F774 Q36041205-40AEFD18-C8D3-4B9D-9E60-F31A0A3DB410 Q36073708-BEF54FFA-168B-4355-9861-79F1B77EB017 Q36173839-003D424A-F4D0-4BE8-A79D-BE5A79690727 Q36399256-C697E92F-6ACE-4A6D-AF32-6E582B57AF5A Q36513866-0A4A6B6F-2A0B-4AE0-A40A-224658BF1B9C Q36513887-B89E2101-FBE8-4F78-847A-07531F21FF3C Q36546544-07D1AFD3-83FC-4852-B42E-BA21006D4812 Q36849465-CA3D6934-259D-4F3F-8094-08E7EFC398D1 Q37368282-75C3CC89-5917-4F19-B1A3-B409BC12F440 Q37620557-672D3FC1-F637-43EB-86A1-C09AF3EE0F7D Q37745098-C2C29995-14CD-4EAC-973E-94A4C31E718E Q37745474-93122D91-DE4A-44F2-B96E-B8D070EB9A02 Q39266426-595011C4-0AF2-4795-B5BD-A2DF9831883B Q39458550-56CFDBDB-6975-44ED-AF57-0E0CB0B4C7E2 Q42100322-599D2F69-D6DF-4785-9CE2-4E0D7CB15948

P2860

ATX-LPA receptor axis in inflammation and cancer.

http://www.wikidata.org/entity/Q34199719

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

name

ATX-LPA receptor axis in inflammation and cancer.

@ast

ATX-LPA receptor axis in inflammation and cancer.

@en

ATX-LPA receptor axis in inflammation and cancer.

@nl

type

label

ATX-LPA receptor axis in inflammation and cancer.

@ast

ATX-LPA receptor axis in inflammation and cancer.

@en

ATX-LPA receptor axis in inflammation and cancer.

@nl

prefLabel

ATX-LPA receptor axis in inflammation and cancer.

@ast

ATX-LPA receptor axis in inflammation and cancer.

@en

ATX-LPA receptor axis in inflammation and cancer.

@nl

P1433

Q34199719-0D66037F-09C0-4F84-A007-97D258679FA2

P1476

Q34199719-6E13CAC4-F7C0-429C-AABD-6C06D29D7CFA

P2093

Q34199719-4E6F6F49-76E4-40CC-8BC0-B3533D4DAF8C

Q34199719-5D27C9A9-F6CF-4385-8622-7FA937BC0192

Q34199719-A8514001-BA12-43D2-A372-13B359CF6043

Q34199719-C4D9174B-594B-44BC-97AC-956DD90D2A97

P2860

Q34199719-03834F88-23EF-4DE0-88CB-5769A15D3A13

Q34199719-06A60E52-FCB0-481A-8A0C-7C979EA9D7BE

Q34199719-070BB054-F808-47B6-8CA2-0863D1D599CE

Q34199719-0AFC398E-BA77-4E3E-8D37-C0CDF306B55C

Q34199719-0EE5C58C-B028-4BC9-A2D2-F3D8AF9EA0BD

Q34199719-10318A91-F678-4B5F-BCE2-093C3177EB17

Q34199719-145C1176-0E14-45F2-BC04-E3426AFCDC2E

Q34199719-179C3DBF-4A6B-468A-BF73-1CD0754543DF

Q34199719-17DE9F3A-3F98-4C67-8DDC-FBEA9A67EF47

Q34199719-19EFFE79-A469-435C-8DC3-5F0FEDA9AB17

P304

Q34199719-AAA866D9-A5AE-45A9-BFE3-0197AAFE51B0

P31

Q34199719-0CBD6F74-35A6-47A8-BCF6-3A1A1A9151F9

P356

Q34199719-2912B4C8-C929-4210-92C8-6C2374C03292

P433

Q34199719-8FD68600-EE15-432B-B0A9-42EC7136D712

P478

Q34199719-0A6B1D73-F69E-4DC4-A22F-DFFB7E3367D9

P577

Q34199719-16BB5CB7-FD8A-484F-BF28-E2B6676E6130

P5875

Q34199719-AAEF7014-9CF4-4F27-A5C1-6FA014FCF2E2

P698

Q34199719-46378A93-E9B8-4052-9A91-DC1F7FBED56A

P921

Q34199719-754C3E9A-2C49-46D7-9DBC-1F7E4699927B

P932

Q34199719-CE331136-BAD4-4A6B-9813-F78F7E10CE80

P356

P1433

P1476

ATX-LPA receptor axis in inflammation and cancer.

@en

P2093

Gordon B Mills

http://www.w3.org/2001/XMLSchema#string

Mandi Murph

http://www.w3.org/2001/XMLSchema#string

Nattapon Panupinthu

http://www.w3.org/2001/XMLSchema#string

Shuying Liu

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid

Characterization of a novel subtype of human G protein-coupled receptor for lysophosphatidic acid

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

Identification and characterization of a novel lysophosphatidic acid receptor, p2y5/LPA6

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma

L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin

An Atomic Model of the Interferon-β Enhanceosome

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Molecular portraits of human breast tumours

P304

3695-3701

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.4161/CC.8.22.9937

http://www.w3.org/2001/XMLSchema#string

P433

22

http://www.w3.org/2001/XMLSchema#string

P478

8

http://www.w3.org/2001/XMLSchema#string

P577

2009-11-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

38034607

http://www.w3.org/2001/XMLSchema#string

P698

19855166

http://www.w3.org/2001/XMLSchema#string

P921

P932

4166520

http://www.w3.org/2001/XMLSchema#string