The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.
about
Viral Interactions with PDZ Domain-Containing Proteins-An Oncogenic Trait?APPL endosomes are not obligatory endocytic intermediates but act as stable cargo-sorting compartments.GAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathwaysPhosphorylation and Internalization of Lysophosphatidic Acid Receptors LPA1, LPA2, and LPA3.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Molecular regulation of lysophosphatidic acid receptor 1 trafficking to the cell surface.Cross-talk between lysophosphatidic acid receptor 1 and tropomyosin receptor kinase A promotes lung epithelial cell migration.A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling.Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments.Comparative analyses of lysophosphatidic acid receptor-mediated signaling.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.APPL1 is a multifunctional endosomal signaling adaptor protein.The GIPC1-Akt1 Pathway Is Required for the Specification of the Eye Field in Mouse Embryonic Stem CellsNeuropilin-1 (NRP-1)/GIPC1 pathway mediates glioma progression.MYO6 Regulates Spatial Organization of Signaling Endosomes Driving AKT Activation and Actin Dynamics.α5β1 integrin trafficking and Rac activation are regulated by APPL1 in a Rab5-dependent manner to inhibit cell migration.The neuropilin 2 isoform NRP2b uniquely supports TGFβ-mediated progression in lung cancer.The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.
P2860
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P2860
The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.
description
2012 nî lūn-bûn
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2012 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@ast
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
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The PDZ protein GIPC regulates ...... es the cell's response to LPA.
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type
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The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@ast
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@en
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@nl
prefLabel
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@ast
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@en
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
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P2093
P2860
P1433
P1476
The PDZ protein GIPC regulates ...... es the cell's response to LPA.
@en
P2093
Oscar Y Baterina
Vanessa Taupin
P2860
P304
P356
10.1371/JOURNAL.PONE.0049227
P407
P577
2012-11-08T00:00:00Z