Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome - Wikidata - awgldk - TriplyDB

Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

http://www.wikidata.org/entity/Q34200046

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Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95 Characterizing autism spectrum disorders by key biochemical pathways.Activity dependent CAM cleavage and neurotransmission Altered Neuronal and Circuit Excitability in Fragile X Syndrome.Emerging pharmacologic treatment options for fragile X syndrome Dendritic spine dysgenesis in autism related disorders The contribution of inhibitory interneurons to circuit dysfunction in Fragile X Syndrome Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Review of targeted treatments in fragile X syndrome A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Auditory processing in fragile x syndrome.Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders Spatiotemporal dynamics of dendritic spines in the living brain.A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination Longitudinal in vivo two-photon fluorescence imaging.Glutamate induces the elongation of early dendritic protrusions via mGluRs in wild type mice, but not in fragile X mice.Two-photon in vivo imaging of dendritic spines in the mouse cortex using a thinned-skull preparation.Structural plasticity: mechanisms and contribution to developmental psychiatric disorders Dendritic spines: from structure to in vivo function Experience-dependent structural plasticity in the cortex.Reversible inhibition of PSD-95 mRNA translation by miR-125a, FMRP phosphorylation, and mGluR signaling.Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly Aberrant frontal lobe maturation in adolescents with fragile X syndrome is related to delayed cognitive maturation Single-Molecule Imaging of PSD-95 mRNA Translation in Dendrites and Its Dysregulation in a Mouse Model of Fragile X Syndrome.The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study Deficit in motor training-induced clustering, but not stabilization, of new dendritic spines in FMR1 knock-out mice Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond.Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1.Experience-dependent plasticity of dendritic spines of layer 2/3 pyramidal neurons in the mouse cortex.Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb.Abnormal intrinsic dynamics of dendritic spines in a fragile X syndrome mouse model in vivo Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo.Impaired synaptic development in a maternal immune activation mouse model of neurodevelopmental disorders Astrocyte-secreted thrombospondin-1 modulates synapse and spine defects in the fragile X mouse model.Delayed dendritic development in newly generated dentate granule cells by cell-autonomous expression of the amyloid precursor protein.Neurotrophin and Wnt signaling cooperatively regulate dendritic spine formation Lynx1 Limits Dendritic Spine Turnover in the Adult Visual Cortex.

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Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome

http://www.wikidata.org/entity/Q34200046

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Dendritic spine instability an ...... se model of fragile X syndrome

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Feng Pan

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Georgina M Aldridge

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Wen-Biao Gan

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William T Greenough

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P2860

The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice.

Stably maintained dendritic spines are associated with lifelong memories

Evidence that fragile X mental retardation protein is a negative regulator of translation

From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome

The fragile X mental retardation protein inhibits translation via interacting with mRNA

Abnormal development of dendritic spines in FMR1 knock-out mice

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