A mathematical framework to determine the temporal sequence of somatic genetic events in cancer
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Computational Cancer Biology: An Evolutionary PerspectiveRecapitulating the Tumor Ecosystem Along the Metastatic Cascade Using 3D Culture ModelsBioinformatics for cancer immunology and immunotherapyCancer evolution: mathematical models and computational inferenceMechanics of the brain: perspectives, challenges, and opportunitiesTemporal ordering of cancer microarray data through a reinforcement learning based approach.Simultaneous inference of cancer pathways and tumor progression from cross-sectional mutation data.CAPRI: efficient inference of cancer progression models from cross-sectional data.Rational design of non-resistant targeted cancer therapiesToward a systematic understanding of cancers: a survey of the pan-cancer studyEpidermal growth factor receptor (EGFR) and prostaglandin-endoperoxide synthase 2 (PTGS2) are prognostic biomarkers for patients with resected colorectal cancer liver metastases.The temporal order of genetic and pathway alterations in tumorigenesis.Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor gliomaA mathematical methodology for determining the temporal order of pathway alterations arising during gliomagenesis.DNA double-strand breaks cooperate with loss of Ink4 and Arf tumor suppressors to generate glioblastomas with frequent Met amplification.What does physics have to do with cancer?Estimating the order of mutations during tumorigenesis from tumor genome sequencing data.Evolutionary pathways in BRCA1-associated breast tumors.Changes in mutational status during third-line treatment for metastatic colorectal cancer--results of consecutive measurement of cell free DNA, KRAS and BRAF in the plasma.Tumor evolutionary directed graphs and the history of chronic lymphocytic leukemiaUsing passenger mutations to estimate the timing of driver mutations and identify mutator alterationsAccurate reconstruction of the temporal order of mutations in neoplastic progressionInferring the temporal order of cancer gene mutations in individual tumor samplesSequencing the AML genome, transcriptome, and epigenome.Identifying restrictions in the order of accumulation of mutations during tumor progression: effects of passengers, evolutionary models, and sampling.Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor responseGenome-wide mutational spectra analysis reveals significant cancer-specific heterogeneityDefining order and timing of mutations during cancer progression: the TO-DAG probabilistic graphical modelActivation of Pim Kinases Is Sufficient to Promote Resistance to MET Small-Molecule Inhibitors.Applying ecological and evolutionary theory to cancer: a long and winding road.Dynamic changes of driver genes' mutations across clinical stages in nine cancer typesAlgorithmic methods to infer the evolutionary trajectories in cancer progression.Methods and challenges in timing chromosomal abnormalities within cancer samples.Cooperative genomic alteration network reveals molecular classification across 12 major cancer types.Genomic profiles of glioma.Malignant glioma: lessons from genomics, mouse models, and stem cells.The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment.Variable selection for disease progression models: methods for oncogenetic trees and application to cancer and HIV.Progression inference for somatic mutations in cancer.Fixation times in differentiation and evolution in the presence of bottlenecks, deserts, and oases
P2860
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P2860
A mathematical framework to determine the temporal sequence of somatic genetic events in cancer
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A mathematical framework to de ...... matic genetic events in cancer
@ast
A mathematical framework to de ...... matic genetic events in cancer
@en
A mathematical framework to de ...... matic genetic events in cancer
@nl
type
label
A mathematical framework to de ...... matic genetic events in cancer
@ast
A mathematical framework to de ...... matic genetic events in cancer
@en
A mathematical framework to de ...... matic genetic events in cancer
@nl
prefLabel
A mathematical framework to de ...... matic genetic events in cancer
@ast
A mathematical framework to de ...... matic genetic events in cancer
@en
A mathematical framework to de ...... matic genetic events in cancer
@nl
P2093
P2860
P356
P1476
A mathematical framework to de ...... matic genetic events in cancer
@en
P2093
Camille Stephan-Otto Attolini
Franziska Michor
Ingo K Mellinghoff
Omar Abdel-Wahab
Rameen Beroukhim
Ross L Levine
Yu-Kang Cheng
P2860
P304
17604-17609
P356
10.1073/PNAS.1009117107
P407
P50
P577
2010-09-23T00:00:00Z