about
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenaseSDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumorsMetabolic, autophagic, and mitophagic activities in cancer initiation and progressionMitochondrial metabolic remodeling in response to genetic and environmental perturbationsHuman Metabolic Enzymes Deficiency: A Genetic Mutation Based ApproachDecoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chainSuccinate Dehydrogenase Loss in Familial Paraganglioma: Biochemistry, Genetics, and EpigeneticsTumors of the neural crest: Common themes in development and cancerPhysiological consequences of complex II inhibition for aging, disease, and the mKATP channelIDH mutations in tumorigenesis and their potential role as novel therapeutic targets.The LYR factors SDHAF1 and SDHAF3 mediate maturation of the iron-sulfur subunit of succinate dehydrogenaseOncometabolites: Unconventional triggers of oncogenic signalling cascadesRole of mitochondrial dysfunction in cancer progressionMitochondria and cancerCurrent views on cell metabolism in SDHx-related pheochromocytoma and paragangliomaSDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanomaDOTS-Finder: a comprehensive tool for assessing driver genes in cancer genomes.Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release.Cancer-associated isocitrate dehydrogenase 1 (IDH1) R132H mutation and d-2-hydroxyglutarate stimulate glutamine metabolism under hypoxia.Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressorsOncometabolites: linking altered metabolism with cancer.Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stressSpatial distribution of cellular function: the partitioning of proteins between mitochondria and the nucleus in MCF7 breast cancer cellsCowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation.High molecular weight forms of mammalian respiratory chain complex IIMultiple susceptibility loci for radiation-induced mammary tumorigenesis in F2[Dahl S x R]-intercross rats.GSTT1 copy number gain and ZNF overexpression are predictors of poor response to imatinib in gastrointestinal stromal tumorsSuccinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism.Polymorphisms in Genes of Tricarboxylic Acid Cycle Key Enzymes Are Associated with Early Recurrence of Hepatocellular Carcinoma.Oxygen concentration controls epigenetic effects in models of familial paraganglioma.Alterations of metabolic genes and metabolites in cancer.LASS5 Interacts with SDHB and Synergistically Represses p53 and p21 ActivityGenetic variations in genes of metabolic enzymes predict postoperational prognosis of patients with colorectal cancer.Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.Mechanistic insights into the regulation of metabolic enzymes by acetylationMitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactionsStructural basis for malfunction in complex II.A novel germline mutation in SDHA identified in a rare case of gastrointestinal stromal tumor complicated with renal cell carcinoma.Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiencyCounseling patients with succinate dehydrogenase subunit defects: genetics, preventive guidelines, and dealing with uncertainty.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
SDH mutations in cancer.
@ast
SDH mutations in cancer.
@en
SDH mutations in cancer.
@nl
type
label
SDH mutations in cancer.
@ast
SDH mutations in cancer.
@en
SDH mutations in cancer.
@nl
prefLabel
SDH mutations in cancer.
@ast
SDH mutations in cancer.
@en
SDH mutations in cancer.
@nl
P1476
SDH mutations in cancer.
@en
P2093
Chiara Bardella
Patrick J Pollard
P304
P356
10.1016/J.BBABIO.2011.07.003
P407
P577
2011-07-13T00:00:00Z