Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation. - Wikidata - awgldk - TriplyDB

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

http://www.wikidata.org/entity/Q34202062

about

Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium Gene of the month: SMARCB1 Epithelioid Sarcoma: Opportunities for Biology-Driven Targeted Therapy ATP-dependent chromatin remodeling complexes as novel targets for cancer therapy SWI/SNF chromatin remodeling complexes and cancer Reverse genetic analysis of the yeast RSC chromatin remodeler reveals a role for RSC3 and SNF5 homolog 1 in ploidy maintenance SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation Generation of a mouse model of atypical teratoid/rhabdoid tumor of the central nervous system through combined deletion of Snf5 and p53.Nonnegative matrix factorization: an analytical and interpretive tool in computational biology.Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes Molecular pathology of sarcomas: concepts and clinical implications Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of rhabdoid tumors.Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen.Rhabdoid tumor: gene expression clues to pathogenesis and potential therapeutic targets.Diverse roles and interactions of the SWI/SNF chromatin remodeling complex revealed using global approaches.Chromatin-regulating proteins as targets for cancer therapy.BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer Epigenetic antagonism between polycomb and SWI/SNF complexes during oncogenic transformation The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation.The limitations of simple gene set enrichment analysis assuming gene independence.An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas.Mechanisms by which SMARCB1 loss drives rhabdoid tumor growth.The chromatin remodelling component SMARCB1/INI1 influences the metastatic behavior of colorectal cancer through a gene signature mapping to chromosome 22.SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.The role of genetics in the establishment and maintenance of the epigenome.SNF5 is an essential executor of epigenetic regulation during differentiation.Congenital anomalies and rhabdoid tumor associated with 22q11 germline deletion and somatic inactivation of the SMARCB1 tumor suppressor.Early expression of the Helicase-Like Transcription Factor (HLTF/SMARCA3) in an experimental model of estrogen-induced renal carcinogenesis.Fibroblast growth factor receptors as novel therapeutic targets in SNF5-deleted malignant rhabdoid tumors p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors.Promiscuous partnerships in Ewing's sarcoma.TCR-dependent transformation of mature memory phenotype T cells in mice.Rhabdoid Variant of Myoepithelial Carcinoma, with EWSR1 Rearrangement: Expanding the Spectrum of EWSR1-Rearranged Myoepithelial Tumors.SWItching on the transcriptional circuitry in melanoma.Chromatin structure following UV-induced DNA damage-repair or death?Metagene projection for cross-platform, cross-species characterization of global transcriptional states Chromatin Remodelers: From Function to Dysfunction.The chromatin remodeling and mRNA splicing functions of the Brahma (SWI/SNF) complex are mediated by the SNR1/SNF5 regulatory subunit.

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P2860

Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation.

http://www.wikidata.org/entity/Q34202062

description

2005 nî lūn-bûn

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2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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type

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... ss in oncogenic transformation

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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Inactivation of the Snf5 tumor ...... s in oncogenic transformation.

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PNAS.0509014102

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Proceedings of the National Academy of Sciences of the United States of America

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Inactivation of the Snf5 tumor ...... ss in oncogenic transformation

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P2093

Aravind Subramanian

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Christine M Fillmore

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Jaclyn A Biegel

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Jill P Mesirov

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Julia A Evans

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Michael S Isakoff

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Pablo Tamayo

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Scott L Pomeroy

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Xi Wang

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P2860

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

Cell cycle arrest and repression of cyclin D1 transcription by INI1/hSNF5.

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

Germline INI1 mutation in a patient with a central nervous system atypical teratoid tumor and renal rhabdoid tumor

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

Germ-line and acquired mutations of INI1 in atypical teratoid and rhabdoid tumors

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

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17745-17750

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10.1073/PNAS.0509014102

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49

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102

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Courtney G Sansam

Charles W Roberts

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7466320

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16301525

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