Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay
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Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryChemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiaeAminoglycosides, but not PTC124 (Ataluren), rescue nonsense mutations in the leptin receptor and in luciferase reporter genes.Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells.Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.PharmGKB summary: very important pharmacogene information for CFTRNMD: At the crossroads between translation termination and ribosome recycling.From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations.Targeting Nonsense Mutations in Diseases with Translational Read-Through-Inducing Drugs (TRIDs).A peptide from human β thymosin as a platform for the development of new anti-biofilm agents for Staphylococcus spp. and Pseudomonas aeruginosa.Paracentrin 1, a synthetic antimicrobial peptide from the sea-urchin Paracentrotus lividus, interferes with staphylococcal and Pseudomonas aeruginosa biofilm formation.Simultaneous reduction of MAD2 and BUBR1 expression induces mitotic spindle alterations associated with p53 dependent cell cycle arrest and death.Ataluren for the treatment of cystic fibrosis.A new compound heterozygous CFTR mutation in a Chinese family with cystic fibrosis.Advances in therapeutic use of a drug-stimulated translational readthrough of premature termination codons.Tautomeric-Dependent Lactam Cycloaddition with Nitrile Oxide: Facile Synthesis of 1,2,4-Oxadiazole[4,5-a]indolone Derivatives.Photo-inhibition of Aβ fibrillation mediated by a newly designed fluorinated oxadiazoleQuaternary structures of GroEL and naïve-Hsp60 chaperonins in solution: a combined SAXS-MD study
P2860
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P2860
Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay
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2014 nî lūn-bûn
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2014 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2014 թվականի փետրվարին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@ast
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@en
Toward a rationale for the PTC124
@nl
type
label
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@ast
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@en
Toward a rationale for the PTC124
@nl
prefLabel
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@ast
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@en
Toward a rationale for the PTC124
@nl
P2093
P2860
P50
P356
P1476
Toward a rationale for the PTC ...... GFP-reporter cell-based assay
@en
P2093
Angelo Spinello
Laura Lentini
Raffaella Melfi
P2860
P304
P356
10.1021/MP400230S
P407
P577
2014-02-07T00:00:00Z