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Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implicationsPhosphoinositides: tiny lipids with giant impact on cell regulationEngineering of an isolated p110α subunit of PI3Kα permits crystallization and provides a platform for structure-based drug designDiscovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity.PI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen PeroxideEpidermal Growth Factor Receptor Cell Proliferation Signaling PathwaysExpression of the RAE-1 family of stimulatory NK-cell ligands requires activation of the PI3K pathway during viral infection and transformation.Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity.Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma.Development and application of PI3K assays for novel drug discovery.The ubiquitin-proteasome system meets angiogenesis.Blocking p55PIK signaling inhibits proliferation and induces differentiation of leukemia cells.Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines.Type I to type II ovarian carcinoma progression: mutant Trp53 or Pik3ca confers a more aggressive tumor phenotype in a mouse model of ovarian cancer.Melatonin-Mediated Intracellular Insulin during 2-Deoxy-d-glucose Treatment Is Reduced through Autophagy and EDC3 Protein in Insulinoma INS-1E Cells.Intracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target?Multiple roles for the p85α isoform in the regulation and function of PI3K signalling and receptor trafficking.AKT-independent PI3-K signaling in cancer - emerging role for SGK3.The role of the dysfunctional akt-related pathway in cancer: establishment and maintenance of a malignant cell phenotype, resistance to therapy, and future strategies for drug development.Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy.Pharmacological classes that extend lifespan of Caenorhabditis elegansPIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer.Phosphoinositide 3-kinase beta controls replication factor C assembly and function.Systematic Analysis of Endometrial Cancer-Associated Hub Proteins Based on Text MiningA butterfly effect in cancer.Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells.Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.HTLV-I Tax regulates the cellular proliferation through the down-regulation of PIP3-phosphatase expressions via the NF-κB pathwayInsights into the pathological mechanisms of p85α mutations using a yeast-based phosphatidylinositol 3-kinase modelGene-Diet Interactions on Colorectal Cancer RiskIdentification of the Binding Sites on Rab5 and p110beta Phosphatidylinositol 3-kinase.Pik3ca is required for mouse uterine gland development and pregnancy.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphatidylinositol 3-kinase: the oncoprotein.
@ast
Phosphatidylinositol 3-kinase: the oncoprotein.
@en
Phosphatidylinositol 3-kinase: the oncoprotein.
@nl
type
label
Phosphatidylinositol 3-kinase: the oncoprotein.
@ast
Phosphatidylinositol 3-kinase: the oncoprotein.
@en
Phosphatidylinositol 3-kinase: the oncoprotein.
@nl
prefLabel
Phosphatidylinositol 3-kinase: the oncoprotein.
@ast
Phosphatidylinositol 3-kinase: the oncoprotein.
@en
Phosphatidylinositol 3-kinase: the oncoprotein.
@nl
P2093
P2860
P50
P356
P1476
Phosphatidylinositol 3-kinase: the oncoprotein.
@en
P2093
Adam Denley
Andreas G Bader
Marco Gymnopoulos
Sohye Kang
P2860
P304
P356
10.1007/82_2010_80
P577
2010-01-01T00:00:00Z