The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.
about
P1433
The aflatoxin B(1) formamidopyrimidine adduct plays a major role in causing the types of mutations observed in human hepatocellular carcinomaTrans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesisARID2: a new tumor suppressor gene in hepatocellular carcinomaDiscriminating different classes of toxicants by transcript profilingMammalian models of chemically induced primary malignancies exploitable for imaging-based preclinical theragnostic researchHarnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinomaStructural Perturbations Induced by the α-Anomer of the Aflatoxin B 1 Formamidopyrimidine Adduct in Duplex and Single-Strand DNABypass of Aflatoxin B 1 Adducts by the Sulfolobus solfataricus DNA Polymerase IVIndoor mold, toxigenic fungi, and Stachybotrys chartarum: infectious disease perspective249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients.AFB1 hepatocarcinogenesis is via lipid peroxidation that inhibits DNA repair, sensitizes mutation susceptibility and induces aldehyde-DNA adducts at p53 mutational hotspot codon 249Chemical Biology of N5-Substituted Formamidopyrimidine DNA Adducts.Molecular genetics of hepatocellular neoplasia.Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention.Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adductBenzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiologyC. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiencyFrom chronic liver disorders to hepatocellular carcinoma: Molecular and genetic pathways.Heme enzyme structure and function.An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.DNA Sequence Modulates Geometrical Isomerism of the trans-8,9- Dihydro-8-(2,6-diamino-4-oxo-3,4-dihydropyrimid-5-yl-formamido)- 9-hydroxy Aflatoxin B1 AdductDNA adducts, detected by 32P postlabelling, in human cholangiocarcinoma.Characterization and Safety of Uniform Particle Size NovaSil Clay as a Potential Aflatoxin EnterosorbentNoncovalent DNA binding drives DNA alkylation by leinamycin: evidence that the Z,E-5-(thiazol-4-yl)-penta-2,4-dienone moiety of the natural product serves as an atypical DNA intercalator.Next-generation sequencing reveals the biological significance of the N(2),3-ethenoguanine lesion in vivoHealth effects of mycotoxins: a toxicological overview.Hepatocellular carcinoma: focus on different aspects of managementOxidative DNA damage in peripheral leukocytes and its association with expression and polymorphisms of hOGG1: a study of adolescents in a high risk region for hepatocellular carcinoma in ChinaDNA-reactive carcinogens: mode of action and human cancer hazard.Pathogen-driven gastrointestinal cancers: Time for a change in treatment paradigm?Specific mutations of hepatitis B virus in plasma predict liver cancer development.An overview of molecular epidemiology of hepatitis B virus (HBV) in IndiaAflatoxin-mediated Sperm and Blood Cell Abnormalities in Mice Fed with Contaminated Corn.Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide.Fragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea.In vitro recapitulating of TP53 mutagenesis in hepatocellular carcinoma associated with dietary aflatoxin B1 exposure.Quantitation of pyridyloxobutyl-DNA adducts in tissues of rats treated chronically with (R)- or (S)-N'-nitrosonornicotine (NNN) in a carcinogenicity study.DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure.AFB(1) -induced mutagenesis of the gpt gene in AS52 cells.
P2860
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P2860
The chemistry and biology of aflatoxin B(1): from mutational spectrometry to carcinogenesis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The chemistry and biology of aflatoxin B
@nl
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@ast
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@en
type
label
The chemistry and biology of aflatoxin B
@nl
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@ast
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@en
prefLabel
The chemistry and biology of aflatoxin B
@nl
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@ast
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@en
P2093
P2860
P356
P1433
P1476
The chemistry and biology of a ...... pectrometry to carcinogenesis.
@en
P2093
Currier SS
Essigmann JM
P2860
P304
P356
10.1093/CARCIN/22.4.535
P407
P577
2001-04-01T00:00:00Z