Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance.
about
Role of the plasma membrane transporter of organic cations OCT1 and its genetic variants in modern liver pharmacologyThe organic anion transporter (OAT) family: a systems biology perspectiveHepatocyte nuclear factor 1 regulates the expression of the organic cation transporter 1 via binding to an evolutionary conserved region in intron 1 of the OCT1 geneOrganic Cation Transporter 1 (OCT1) mRNA expression in hepatocellular carcinoma as a biomarker for sorafenib treatmentCholangiocarcinoma: Biology, Clinical Management, and Pharmacological Perspectives.Hepatocyte SLAMF3 reduced specifically the multidrugs resistance protein MRP-1 and increases HCC cells sensitization to anti-cancer drugs.The lack of the organic cation transporter OCT1 at the plasma membrane of tumor cells precludes a positive response to sorafenib in patients with hepatocellular carcinoma.Physicochemical properties of novel protein kinase inhibitors in relation to their substrate specificity for drug transporters.Prevention of hepatocellular carcinoma by correction of metabolic abnormalities: Role of statins and metformin.Effect of Liver Disease on Hepatic Transporter Expression and Function.Expression of organic cation transporter 1 (OCT1): unique patterns of indirect regulation by nuclear receptors and hepatospecific gene regulation.Expression of SLC22A1 variants may affect the response of hepatocellular carcinoma and cholangiocarcinoma to sorafenib.Long-term cisplatin exposure promotes methylation of the OCT1 gene in human esophageal cancer cells.A proposal regarding reporting of in vitro testing resultsRole of drug-dependent transporter modulation on the chemosensitivity of cholangiocarcinoma.Upregulated SLC22A3 has a potential for improving survival of patients with head and neck squamous cell carcinoma receiving cisplatin treatment.Low SLC29A1 expression is associated with poor prognosis in patients with hepatocellular carcinoma.Transporter expression in non-cancerous and cancerous liver tissue from donors with hepatocellular carcinoma and chronic hepatitis C infection quantified by LC-MS/MS proteomics.Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells.Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.Solute carrier transporters: potential targets for digestive system neoplasms.CD38 Inhibits Prostate Cancer Metabolism and Proliferation by Reducing Cellular NAD Pools
P2860
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P2860
Downregulation of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) in human hepatocellular carcinoma and their prognostic significance.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Downregulation of organic cati ...... their prognostic significance.
@ast
Downregulation of organic cati ...... their prognostic significance.
@en
Downregulation of organic cation transporters OCT1
@nl
type
label
Downregulation of organic cati ...... their prognostic significance.
@ast
Downregulation of organic cati ...... their prognostic significance.
@en
Downregulation of organic cation transporters OCT1
@nl
prefLabel
Downregulation of organic cati ...... their prognostic significance.
@ast
Downregulation of organic cati ...... their prognostic significance.
@en
Downregulation of organic cation transporters OCT1
@nl
P2093
P2860
P356
P1433
P1476
Downregulation of organic cati ...... their prognostic significance
@en
P2093
Anca Zimmermann
Anja Lautem
Arno Schad
Daniel Foltys
Dirk Gründemann
Johanna Knapstein
Marcus Schuchmann
Maria Hoppe-Lotichius
Michael Heise
P2860
P2888
P356
10.1186/1471-2407-12-109
P407
P577
2012-03-22T00:00:00Z
P5875
P6179
1045144732