Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse - Wikidata - awgldk - TriplyDB

Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse

Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse

http://www.wikidata.org/entity/Q34211879

about

Targeting beta-catenin signaling to induce apoptosis in human breast cancer cells by z-guggulsterone and Gugulipid extract of Ayurvedic medicine plant Commiphora mukul.HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance.A genomic analysis of mouse models of breast cancer reveals molecular features of mouse models and relationships to human breast cancer.Axillary metaplastic breast carcinoma with ipsilateral pectoral invasive ductal carcinoma: an unusual presentation Sox2 promotes tamoxifen resistance in breast cancer cells.Wnt pathway activity in breast cancer sub-types and stem-like cells Mammary cells with active Wnt signaling resist ErbB2-induced tumorigenesis Wnt3a expression is associated with MMP-9 expression in primary tumor and metastatic site in recurrent or stage IV colorectal cancer.High basal Wnt signaling is further induced by PI3K/mTor inhibition but sensitive to cSRC inhibition in mammary carcinoma cell lines with HER2/3 overexpression.Bayesian model of signal rewiring reveals mechanisms of gene dysregulation in acquired drug resistance in breast cancer Paracrine Wnt signaling both promotes and inhibits human breast tumor growth.Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.ARF6-regulated endocytosis of growth factor receptors links cadherin-based adhesion to canonical Wnt signaling in epithelia In MMTV-Her-2/neu transgenic mammary tumors the absence of caveolin-1-/- alters PTEN and NHERF1 but not β-catenin expression.Simultaneous disruption of estrogen receptor and Wnt/β-catenin signaling is involved in methyl amooranin-mediated chemoprevention of mammary gland carcinogenesis in rats.miR-139-5p is a regulator of metastatic pathways in breast cancer.Chromatin effector Pygo2 regulates mammary tumor initiation and heterogeneity in MMTV-Wnt1 mice.Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium Potential therapeutic targets of Guggulsterone in cancer Occurrence and significance of epithelial-mesenchymal transition in breast cancer.Par-4 dependent modulation of cellular β-catenin by medicinal plant natural product derivative 3-azido Withaferin A.HER2 and β-catenin protein location: importance in the prognosis of breast cancer patients and their correlation when breast cancer cells suffer stressful situations.Transcriptomic analyses of the anti-adipogenic effects of oleuropein in human mesenchymal stem cells.Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC.Monitoring the HER2 copy number status in circulating tumor DNA by droplet digital PCR in patients with gastric cancer.Endocrine Therapy of Estrogen Receptor-Positive Breast Cancer Cells: Early Differential Effects on Stem Cell Markers.Positive expression of cyclin D1 is an indicator for the evaluation of the prognosis of breast cancer.Comparison of Anticancer Effects of Carbamazepine and Valproic Acid.Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer.High-frequency deregulated expression of Wnt signaling pathway members in breast carcinomas.Role of GSK3β in breast cancer susceptibility.Analysis of wntless (WLS) expression in gastric, ovarian, and breast cancers reveals a strong association with HER2 overexpression.

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P2860

Activation status of Wnt/ß-catenin signaling in normal and neoplastic breast tissues: relationship to HER2/neu expression in human and mouse

http://www.wikidata.org/entity/Q34211879

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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Activation status of Wnt/ß-cat ...... expression in human and mouse

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Activation status of Wnt/ß-cat ...... expression in human and mouse

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Dilip D Giri

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Grace A Tan

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Sara Khalil

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Xi Kathy Zhou

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P2860

Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC

beta-Catenin is a Nek2 substrate involved in centrosome separation.

The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.

Wnt signaling and cancer

Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription

ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas

The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton

The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development

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