about
Therapeutic Targeting of TelomeraseMechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapyCellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationPolyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic StrategiesBiomarkers and molecular probes for cell death imaging and targeted therapeuticsTherapeutic targeting of replicative immortalityCell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition.TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence.Redox control of senescence and age-related diseaseDocetaxel-induced polyploidization may underlie chemoresistance and disease relapseDexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancerRepression of PLA2R1 by c-MYC and HIF-2alpha promotes cancer growthSilencing of protein kinase D2 induces glioma cell senescence via p53-dependent and -independent pathways.Extracellular cystatin SN and cathepsin B prevent cellular senescence by inhibiting abnormal glycogen accumulation.Pentoxifylline sensitizes human cervical tumor cells to cisplatin-induced apoptosis by suppressing NF-kappa B and decreased cell senescence.Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumorsExploiting tumor cell senescence in anticancer therapyAndrogen deprivation induces senescence characteristics in prostate cancer cells in vitro and in vivo5-aza-2'-deoxycytidine-mediated c-myc Down-regulation triggers telomere-dependent senescence by regulating human telomerase reverse transcriptase in chronic myeloid leukemia.Elimination of quiescent/slow-proliferating cancer stem cells by Bcl-XL inhibition in non-small cell lung cancerSimvastatin suppresses breast cancer cell proliferation induced by senescent cellsIdentification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response.Cellular Senescence Promotes Adverse Effects of Chemotherapy and Cancer Relapse.Probing early tumor response to radiation therapy using hyperpolarized [1-¹³C]pyruvate in MDA-MB-231 xenografts.Resveratrol induces premature senescence in lung cancer cells via ROS-mediated DNA damage.Resveratrol enhances ionizing radiation-induced premature senescence in lung cancer cells.MicroRNAs Regulate Key Effector Pathways of SenescenceSIRT1 inactivation evokes antitumor activities in NSCLC through the tumor suppressor p27.The p53-reactivating small molecule RITA induces senescence in head and neck cancer cellsWnt5a suppresses epithelial ovarian cancer by promoting cellular senescence.Overexpression of the novel senescence marker β-galactosidase (GLB1) in prostate cancer predicts reduced PSA recurrenceInsights into 4E-BP1 and p53 mediated regulation of accelerated cell senescenceIonizing radiation-induced foci persistence screen to discover enhancers of accelerated senescence.Treatment-induced cell cycle kinetics dictate tumor response to chemotherapyLong Term Exposure to Polyphenols of Artichoke (Cynara scolymus L.) Exerts Induction of Senescence Driven Growth Arrest in the MDA-MB231 Human Breast Cancer Cell Line.Identification of a Selective G1-Phase Benzimidazolone Inhibitor by a Senescence-Targeted Virtual Screen Using Artificial Neural Networks.The HSP90 Inhibitor Ganetespib Radiosensitizes Human Lung Adenocarcinoma Cells.Shifts in subsets of CD8+ T-cells as evidence of immunosenescence in patients with cancers affecting the lungs: an observational case-control study.AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy.Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Therapy-induced senescence in cancer
@ast
Therapy-induced senescence in cancer
@en
Therapy-induced senescence in cancer
@nl
type
label
Therapy-induced senescence in cancer
@ast
Therapy-induced senescence in cancer
@en
Therapy-induced senescence in cancer
@nl
prefLabel
Therapy-induced senescence in cancer
@ast
Therapy-induced senescence in cancer
@en
Therapy-induced senescence in cancer
@nl
P2093
P2860
P356
P1476
Therapy-induced senescence in cancer
@en
P2093
David F Jarrard
Jonathan A Ewald
Joshua A Desotelle
P2860
P304
P356
10.1093/JNCI/DJQ364
P407
P577
2010-09-21T00:00:00Z