about
Peptidoglycan remodeling by the coordinated action of multispecific enzymesStructural basis for the broad specificity of a new family of amino-acid racemasesMolecular characterization of novel pyridoxal-5′-phosphate-dependent enzymes from the human microbiomeBiochemical Characterization of Glutamate Racemase-A New Candidate Drug Target against Burkholderia cenocepacia InfectionsThe evolution of enzyme function in the isomerases.Structural and Functional Adaptation of Vancomycin Resistance VanT Serine RacemasesDiscovery of a novel amino acid racemase through exploration of natural variation in Arabidopsis thaliana.Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway.Amino acid racemization in Pseudomonas putida KT2440Bacterial synthesis of D-amino acids.Harnessing allostery: a novel approach to drug discovery.Inhibitors of alanine racemase enzyme: a review.Environmental roles of microbial amino acid racemases.The Unexpected Advantages of Using D-Amino Acids for Peptide Self- Assembly into Nanostructured Hydrogels for Medicine.Exploiting racemases.Resistance mechanism to an uncompetitive inhibitor of a single-substrate, single-product enzyme: a study of Helicobacter pylori glutamate racemase.In silico optimization of a fragment-based hit yields biologically active, high-efficiency inhibitors for glutamate racemase.Crystallographic studies of aspartate racemase from Lactobacillus sakei NBRC 15893.Analyses of Arabidopsis ecotypes reveal metabolic diversity to convert D-amino acids.ATP binding to human serine racemase is cooperative and modulated by glycine.Cyclopropane derivatives as potential human serine racemase inhibitors: unveiling novel insights into a difficult target.Alternative Mechanistic Strategy for Enzyme Catalysis in a Ni-Dependent Lactate Racemase (LarA): Intermediate Destabilization by the Cofactor.Hyperpolarization of Nitrogen-15 Schiff Bases by Reversible Exchange Catalysis with para-Hydrogen.Generalizing, Extending, and Maximizing Nitrogen-15 Hyperpolarization Induced by Parahydrogen in Reversible Exchange.Regulation of human serine racemase activity and dynamics by halides, ATP and malonateRecent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosynthesesPhase-transfer enantioselective monoalkylation of prochiral nickel(ii) complexes catalyzed by 3,3′-bis[hydroxy(diphenyl)methyl]-1,1′-binaphthyl-2,23′-diol (BIMBOL) as a route to α-amino acids
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
Drug discovery targeting amino acid racemases.
@ast
Drug discovery targeting amino acid racemases.
@en
Drug discovery targeting amino acid racemases.
@nl
type
label
Drug discovery targeting amino acid racemases.
@ast
Drug discovery targeting amino acid racemases.
@en
Drug discovery targeting amino acid racemases.
@nl
prefLabel
Drug discovery targeting amino acid racemases.
@ast
Drug discovery targeting amino acid racemases.
@en
Drug discovery targeting amino acid racemases.
@nl
P50
P356
P1433
P1476
Drug discovery targeting amino acid racemases.
@en
P2093
Arnaud Blondel
P304
P356
10.1021/CR2000702
P577
2011-09-13T00:00:00Z