Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains. - Wikidata - awgldk - TriplyDB

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains.

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains.

http://www.wikidata.org/entity/Q34216316

about

Structure and function of the two tandem WW domains of the pre-mRNA splicing factor FBP21 (formin-binding protein 21)Alternative initiation and splicing in dicer gene expression in human breast cells Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel Ubiquitylation and control of renal Na+ balance and blood pressure Wrapping up the bad news: HIV assembly and release Specificity and Autoregulation of Notch Binding by Tandem WW Domains in Suppressor of Deltex Deletion of the ubiquitin ligase Nedd4L in lung epithelia causes cystic fibrosis-like disease A human polymorphism affects NEDD4L subcellular targeting by leading to two isoforms that contain or lack a C2 domain Rescue of HIV-1 release by targeting widely divergent NEDD4-type ubiquitin ligases and isolated catalytic HECT domains to Gag.Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.Unique regulation of human Na+/H+ exchanger 3 (NHE3) by Nedd4-2 ligase that differs from non-primate NHE3s.Nedd4-2 isoforms differentially associate with ENaC and regulate its activity.Activation of NHE3 by dexamethasone requires phosphorylation of NHE3 at Ser663 by SGK1 The short isoform of the ubiquitin ligase NEDD4L is a CREB target gene in hepatocytes.The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture.Regulation of NaCl transport in the renal collecting duct: lessons from cultured cells.Efficient and specific rescue of human immunodeficiency virus type 1 budding defects by a Nedd4-like ubiquitin ligase.A functional variant of NEDD4L is associated with obesity and related phenotypes in a Han population of Southern China.AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5'-flanking region of the VIT32 gene.A naturally occurring human Nedd4-2 variant displays impaired ENaC regulation in Xenopus laevis oocytes.

P2860

Q24313388-98297714-8526-45E3-B910-B8DC04988B7E Q24531192-2E36F628-237B-4ECD-9BB4-B1A4ED9F0406 Q24651528-46306026-1EC0-4963-BE44-954D03ADC570 Q24656272-BCEA3211-3B3A-4713-BFB0-5BBF003B4CCE Q24657768-F29F460E-93FE-49DC-81B4-8591ED86F9B0 Q26863205-18751A90-80A6-41A8-B815-CC0A4817729B Q26992150-2C225B6C-739D-4C66-AF75-D89C2EDCD686 Q27646888-301EBE6E-8308-48E6-9A61-64F69EE1611D Q28512734-59594B76-E876-41FE-B3FF-C88B22E9C3B2 Q30487486-D956CB91-4CBA-459D-B87E-78F52E6AED7F Q33700568-D88976EB-62B6-45BB-A494-354FC06D1C84 Q33748196-AD44BBFC-7BFD-4E27-9696-7BDAC25A31FB Q34073881-65D9CAA7-A0A5-4C80-AD39-51DA3BBBDE32 Q34409388-91FB45B3-94A5-4E52-A0DF-F4A42E0D0A16 Q34652990-187415B3-80D6-4436-9068-3773B2AC9CC5 Q35023606-274ABBA2-3B6F-4374-B669-17AAC15D4A41 Q35691527-AE672A17-F94E-411A-9D2A-BA361EDC9FBA Q36579586-2A96B1DA-1111-48F6-84A1-EDD4E1CACD27 Q36594142-B002C89A-BE77-4776-A4EC-4511C723F22E Q36820453-1BB6DB18-056E-434D-BEDC-F4BB16D62985 Q40556590-43A3CE45-0102-4550-ACEF-E765E8CD93FE Q42461529-B682A4E5-6109-4B5E-83E9-DE8E7A6EF105

P2860

Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains.

http://www.wikidata.org/entity/Q34216316

description

2003 nî lūn-bûn

@nan

2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年学术文章

@wuu

2003年学术文章

@zh-cn

2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

name

Alternate promoters and variab ...... varying number of WW domains.

@ast

Alternate promoters and variab ...... varying number of WW domains.

@en

Alternate promoters and variab ...... varying number of WW domains.

@nl

type

label

Alternate promoters and variab ...... varying number of WW domains.

@ast

Alternate promoters and variab ...... varying number of WW domains.

@en

Alternate promoters and variab ...... varying number of WW domains.

@nl

prefLabel

Alternate promoters and variab ...... varying number of WW domains.

@ast

Alternate promoters and variab ...... varying number of WW domains.

@en

Alternate promoters and variab ...... varying number of WW domains.

@nl

P1433

Q34216316-BD320C04-1C4E-4005-9330-BD71AD8D8BF5

P1476

Q34216316-F3455CC3-FFC5-4076-A329-5BB477C7DBAE

P2093

Q34216316-9AA845E4-FD58-4C83-B66A-8AD0B4A80E9A

Q34216316-A5CC5129-C68B-4796-BDE6-91FC4A6F138D

Q34216316-A7216465-950F-494E-BEEF-815CBF9E3535

Q34216316-AC503B34-7491-4617-837B-0AE0D9984633

Q34216316-DE5A88E1-7839-4CFC-867B-6F7C5F294504

P2860

Q34216316-06FAC58E-EE30-40F7-94C9-529D900D0690

Q34216316-0B47D0D7-C862-4DC4-B5B3-FC4DE612B132

Q34216316-0EC8A658-B23F-413F-AF7B-AEE3D7D942E6

Q34216316-1225E6AB-D91E-49CF-B1EF-8FBF2589BC33

Q34216316-159D6C86-CA4E-4DE6-A8B9-2E80A400529B

Q34216316-16CFD7B2-2FC4-4CF5-9461-CA6BB79FC9A9

Q34216316-207C4BF8-E0A1-46D7-A388-A52841960786

Q34216316-22776BE6-32DB-4B7D-92B4-83099CCA5C22

Q34216316-33AADE91-74E3-40FB-B43C-A15D6E95E4FA

Q34216316-45046389-B857-40F0-9F82-AB2503277E67

P304

Q34216316-8E0CCADB-42C5-4F5A-8327-D8D9A178A38F

P31

Q34216316-3C8CDB62-CBF1-4EB7-A705-A1F71C037F81

P356

Q34216316-E31694A1-BADA-41E9-A84E-D850A324993C

P433

Q34216316-21B48B81-5ACD-45AE-96E7-306DAE12B551

P478

Q34216316-7245120E-572F-4712-A5F3-A75AE75A5B29

P577

Q34216316-71F49EF0-1B9B-4398-BA8A-E8B35B7C1882

P5875

Q34216316-9F235309-7381-4727-9DAF-10D9023B27E3

P698

Q34216316-96FFDBC5-7D0A-41B8-AE9A-C0B68C27DFA4

P356

AJPRENAL.00203.2003

P1433

American Journal of Physiology - Renal Physiology

P1476

Alternate promoters and variab ...... varying number of WW domains.

@en

P2093

Christie P Thomas

http://www.w3.org/2001/XMLSchema#string

Jason R Campbell

http://www.w3.org/2001/XMLSchema#string

Juan Herrero

http://www.w3.org/2001/XMLSchema#string

Omar A Itani

http://www.w3.org/2001/XMLSchema#string

Peter M Snyder

http://www.w3.org/2001/XMLSchema#string

P2860

Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits

The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel

The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

Identification of novel human WW domain-containing proteins by cloning of ligand targets

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb

Structure of the first C2 domain of synaptotagmin I: a novel Ca2+/phospholipid-binding fold

All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+

Multiple WW domains, but not the C2 domain, are required for inhibition of the epithelial Na+ channel by human Nedd4

P304

F916-29

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/AJPRENAL.00203.2003

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

285

http://www.w3.org/2001/XMLSchema#string

P577

2003-07-22T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

10649099

http://www.w3.org/2001/XMLSchema#string

P698

12876068

http://www.w3.org/2001/XMLSchema#string