TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival
about
Crystal structure of the epithelial calcium channel TRPV6First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors.STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis.Lidocaine inhibits the invasion and migration of TRPV6-expressing cancer cells by TRPV6 downregulation.Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling.STIM and ORAI proteins: crucial roles in hallmarks of cancer.Role of TRP ion channels in cancer and tumorigenesis.Bcl-2 proteins and calcium signaling: complexity beneath the surface.Functional role of TRP channels in modulating ER stress and Autophagy.Optimization of TRPV6 Calcium Channel Inhibitors Using a 3D Ligand-Based Virtual Screening Method.The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition.The role of extracellular calcium in bone metastasis.Targeting calcium signaling in cancer therapy.Constitutive calcium entry and cancer: updated views and insights.The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.TRPV6 modulates proliferation of human pancreatic neuroendocrine BON-1 tumour cells.Resveratrol attenuates high glucose-induced endothelial cell apoptosis via mediation of store-operated calcium entry.Overexpression of calcyphosine is associated with poor prognosis in esophageal squamous cell carcinoma.Calcium and Nuclear Signaling in Prostate Cancer.Ion Permeation Mechanism in Epithelial Calcium Channel TRVP6.TRPC6 Channels Are Required for Proliferation, Migration and Invasion of Breast Cancer Cell Lines by Modulation of Orai1 and Orai3 Surface ExposureInhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model
P2860
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P2860
TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
TRPV6 calcium channel transloc ...... controls cancer cell survival
@ast
TRPV6 calcium channel transloc ...... controls cancer cell survival
@en
TRPV6 calcium channel transloc ...... controls cancer cell survival
@nl
type
label
TRPV6 calcium channel transloc ...... controls cancer cell survival
@ast
TRPV6 calcium channel transloc ...... controls cancer cell survival
@en
TRPV6 calcium channel transloc ...... controls cancer cell survival
@nl
prefLabel
TRPV6 calcium channel transloc ...... controls cancer cell survival
@ast
TRPV6 calcium channel transloc ...... controls cancer cell survival
@en
TRPV6 calcium channel transloc ...... controls cancer cell survival
@nl
P2093
P2860
P50
P356
P1476
TRPV6 calcium channel transloc ...... controls cancer cell survival
@en
P2093
Adriana Mihalache
Alexandre Bokhobza
Benjamin Beck
Fabien Vanden Abeele
Leonardo Farsetti
Matthieu Vandenberghe
Maylis Raphaël
Pierre Gosset
Roman Skryma
Sergiy Khalimonchyk
P2860
P304
P356
10.1073/PNAS.1413409111
P407
P577
2014-08-29T00:00:00Z