Clinical significance of Polycomb gene expression in brain tumors.
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Phosphorylation of EZH2 activates STAT3 signaling via STAT3 methylation and promotes tumorigenicity of glioblastoma stem-like cellsEZH2 is highly expressed in pituitary adenomas and associated with proliferationDiverse involvement of EZH2 in cancer epigeneticsUnique anti-glioblastoma activities of hypericin are at the crossroad of biochemical and epigenetic events and culminate in tumor cell differentiationDistinct and separable roles for EZH2 in neurogenic astrogliaRegulation and Role of EZH2 in CancerAntitumor effects of pharmacological EZH2 inhibition on malignant peripheral nerve sheath tumor through the miR-30a and KPNB1 pathway.Inactivation of X-linked tumor suppressor genes in human cancer.Transcriptional network analysis reveals that AT1 and AT2 angiotensin II receptors are both involved in the regulation of genes essential for glioma progression.MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma.HOTAIR is a therapeutic target in glioblastoma.Role of epigenetic modifications in luminal breast cancer.Targeting the enhancer of zeste homologue 2 in medulloblastoma.Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer.Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects.Epigenetic changes in pediatric solid tumors: promising new targets.Evaluation of histone 3 lysine 27 trimethylation (H3K27me3) and enhancer of Zest 2 (EZH2) in pediatric glial and glioneuronal tumors shows decreased H3K27me3 in H3F3A K27M mutant glioblastomas.Treatment resistance mechanisms of malignant glioma tumor stem cellsEZH2 inhibition: targeting the crossroad of tumor invasion and angiogenesis.Epigenetic modification in gliomas: role of the histone methyltransferase EZH2.The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?Context-dependent actions of Polycomb repressors in cancer.MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells.Suppressor of Zeste 12 homolog RNA interference inhibits retinoblastoma cell invasion.Epigenetic Mechanisms of Tamoxifen Resistance in Luminal Breast Cancer.Histone code, human growth and cancerElevated expression of a pharmacologic Polycomb signature predicts poor prognosis in gastric and breast cancer.Development and validation of reagents and assays for EZH2 peptide and nucleosome high-throughput screens.Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes.The role of EZH2 in overall survival of colorectal cancer: a meta-analysis.MicroRNA in Glioblastoma: An Overview.The EZH2 inhibitor GSK343 suppresses cancer stem-like phenotypes and reverses mesenchymal transition in glioma cells.EZH2 orchestrates apicobasal polarity and neuroepithelial cell renewal.Clinicopathological features of primary diffuse large B-cell lymphoma of the central nervous system - strong EZH2 expression implying diagnostic and therapeutic implication.Mining Massive Amounts of Genomic Data: A Semiparametric Topic Modeling Approach
P2860
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P2860
Clinical significance of Polycomb gene expression in brain tumors.
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Clinical significance of Polycomb gene expression in brain tumors.
@ast
Clinical significance of Polycomb gene expression in brain tumors.
@en
Clinical significance of Polycomb gene expression in brain tumors.
@nl
type
label
Clinical significance of Polycomb gene expression in brain tumors.
@ast
Clinical significance of Polycomb gene expression in brain tumors.
@en
Clinical significance of Polycomb gene expression in brain tumors.
@nl
prefLabel
Clinical significance of Polycomb gene expression in brain tumors.
@ast
Clinical significance of Polycomb gene expression in brain tumors.
@en
Clinical significance of Polycomb gene expression in brain tumors.
@nl
P2860
P356
P1433
P1476
Clinical significance of Polycomb gene expression in brain tumors
@en
P2093
Elaine M Hurt
William L Farrar
P2860
P2888
P356
10.1186/1476-4598-9-265
P577
2010-09-30T00:00:00Z
P5875
P6179
1051845270