Loss of ceramide synthase 3 causes lethal skin barrier disruption. - Wikidata - awgldk - TriplyDB

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

http://www.wikidata.org/entity/Q34228817

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Mutations in CERS3 cause autosomal recessive congenital ichthyosis in humans Ceramide synthases at the centre of sphingolipid metabolism and biology Autophagy paradox and ceramide On the future of mass-spectrometry-based lipidomics Ceramide synthesis regulates T cell activity and GVHD development.Metabolism of very long-chain Fatty acids: genes and pathophysiology.Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation.Cooperative Synthesis of Ultra Long-Chain Fatty Acid and Ceramide during Keratinocyte Differentiation.Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.Skin lipids: localization of ceramide and fatty acid in the unit cell of the long periodicity phase.Detection of QTL controlling feed efficiency and excretion in chickens fed a wheat-based diet.Improved epidermal barrier formation in human skin models by chitosan modulated dermal matrices.A fluorescent assay for ceramide synthase activity.Altered epidermal lipid processing and calcium distribution in the KID syndrome mouse model Cx26S17F.Ablation of ceramide synthase 2 causes chronic oxidative stress due to disruption of the mitochondrial respiratory chain Ceramide Synthase 5 Is Essential to Maintain C16:0-Ceramide Pools and Contributes to the Development of Diet-induced Obesity.Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production Skin Immunity to Candida albicans.Construction of conditional acid ceramidase knockout mice and in vivo effects on oocyte development and fertility.1-O-acylceramides are natural components of human and mouse epidermis PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis.Epidermal barriers Human genetic disorders of sphingolipid biosynthesis.Sphingolipids and mitochondrial apoptosis.Targeting sphingolipid metabolism in the treatment of obesity/type 2 diabetes.Sphingosine-1-phosphate as signaling molecule in the skin: Relevance in atopic dermatitis.Ceramide and Its Related Neurochemical Networks as Targets for Some Brain Disorder Therapies.The Herbal Bitter Drug Gentiana lutea Modulates Lipid Synthesis in Human Keratinocytes In Vitro and In Vivo.Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein.PNPLA1 defects in patients with autosomal recessive congenital ichthyosis and KO mice sustain PNPLA1 irreplaceable function in epidermal omega-O-acylceramide synthesis and skin permeability barrier.Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea.Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer.Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region.Autosomal recessive congenital ichthyosis: CERS3 mutations identified by a next generation sequencing panel targeting ichthyosis genes.Genome-wide DNA methylation analysis in blood cells from patients with Werner syndrome PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide.Lorenzo's oil inhibits ELOVL1 and lowers the level of sphingomyelin with a saturated very long-chain fatty acid Glycosphingolipids are essential for intestinal endocytic function.Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation.

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P2860

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

http://www.wikidata.org/entity/Q34228817

description

2011 nî lūn-bûn

@nan

2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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type

label

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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Loss of ceramide synthase 3 causes lethal skin barrier disruption.

@nl

prefLabel

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

@ast

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

@en

Loss of ceramide synthase 3 causes lethal skin barrier disruption.

@nl

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Human Molecular Genetics

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Loss of ceramide synthase 3 causes lethal skin barrier disruption.

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Alexander Dalpke

http://www.w3.org/2001/XMLSchema#string

Aline Bayerle

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Franciscus van der Hoeven

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Hermann-Josef Gröne

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Joachim Kirsch

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Karin Gorgas

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Klaus Willecke

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Mariona Rabionet

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Richard Jennemann

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Roger Sandhoff

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10.1093/HMG/DDR494

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3

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22038835

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Ceramide synthase 3

sphingosine N-acyltransferase activity

Ceramide synthase 3