A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells.
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Interleukin-2 receptor signaling: at the interface between tolerance and immunitymTOR inhibitors effects on regulatory T cells and on dendritic cellsInducing and Administering Tregs to Treat Human DiseaseCellular and molecular determinants for the development of natural and induced regulatory T cellsHomeostasis and function of regulatory T cells in agingRoles of TRAF3 in T cells: many surprisesThe importance of regulatory T-cell heterogeneity in maintaining self-toleranceManipulating IL-2 availability amid presentation of donor MHC antigens suppresses murine alloimmune responses by inducing regulatory T cells.Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjectsUltra-low dose interleukin-2 promotes immune-modulating function of regulatory T cells and natural killer cells in healthy volunteers.Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression.IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells.The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2.T cells as therapeutic targets in SLE.CD4(+) CD25(+) Foxp3(+) T regulatory cells with limited TCR diversity in control of autoimmunity.Ectonucleotidase CD38 demarcates regulatory, memory-like CD8+ T cells with IFN-γ-mediated suppressor activities.Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)Beyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.IL-2Rβ-dependent signaling and CD103 functionally cooperate to maintain tolerance in the gut mucosa.An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness.Unexpected modulation of recall B and T cell responses after immunization with rotavirus-like particles in the presence of LT-R192G.T cells as a therapeutic target in SLE.Pathogenesis and potential therapeutic targets in systemic lupus erythematosus: from bench to bedsideCCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in miceFunctional Modulation of Regulatory T Cells by IL-2.The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development.Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules.Quorum-Sensing in CD4(+) T Cell Homeostasis: A Hypothesis and a Model.Interleukin-2 activity can be fine tuned with engineered receptor signaling clamps.IL2RA is associated with persistence of rheumatoid arthritis.Treg cells, life history, and diversityA Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression.DUSP4 deficiency enhances CD25 expression and CD4+ T-cell proliferation without impeding T-cell development.Cytokines of the γ(c) family control CD4+ T cell differentiation and function.Developmental Progression and Interrelationship of Central and Effector Regulatory T Cell Subsets.Thymic versus induced regulatory T cells - who regulates the regulators?Update on use of aldesleukin for treatment of high-risk metastatic melanoma.Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.Short-term intratracheal use of PEG-modified IL-2 and glucocorticoid persistently alleviates asthma in a mouse model.IL-2 coordinates IL-2-producing and regulatory T cell interplay.
P2860
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P2860
A low interleukin-2 receptor signaling threshold supports the development and homeostasis of T regulatory cells.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@ast
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@en
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@nl
type
label
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@ast
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@en
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@nl
prefLabel
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@ast
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@en
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@nl
P2093
P2860
P1433
P1476
A low interleukin-2 receptor s ...... ostasis of T regulatory cells.
@en
P2093
Linjian Zhu
Norman H Altman
Thomas R Malek
P2860
P304
P356
10.1016/J.IMMUNI.2008.11.014
P407
P577
2009-01-29T00:00:00Z