Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis.
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Cartilage and bone metabolism in rheumatoid arthritis. Differences between rapid and slow progression of disease identified by serum markers of cartilage metabolismStructure and function of aggrecan.Association of rs9340799 polymorphism in estrogen receptor alpha gene with the risk of osteoarthritis: evidence based on 8,792 subjects.Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health.High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis.Elevation of a collagenase generated type II collagen neoepitope and proteoglycan epitopes in synovial fluid following induction of joint instability in the dogBiomarkers of antioxidant status, inflammation, and cartilage metabolism are affected by acute intense exercise but not superoxide dismutase supplementation in horses.Dwarfism and age-associated spinal degeneration of heterozygote cmd mice defective in aggrecan.The role of aggrecan in normal and osteoarthritic cartilage.Serum CTXii Correlates With Articular Cartilage Degeneration After Anterior Cruciate Ligament Transection or Arthrotomy Followed by Standardized Exercise.Cartilage markers and their association with cartilage loss on magnetic resonance imaging in knee osteoarthritis: the Boston Osteoarthritis Knee Study.Application of biomarkers in the clinical development of new drugs for chondroprotection in destructive joint diseases: a review.Serum protein signatures detect early radiographic osteoarthritis.Inflammatory mediators and cartilage biomarkers in synovial fluid after a single inflammatory insult: a longitudinal experimental studySynovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study.Aggrecan is degraded by matrix metalloproteinases in human arthritis. Evidence that matrix metalloproteinase and aggrecanase activities can be independent.Evidence for altered synthesis of type II collagen in patients with osteoarthritis.Loss of extracellular matrix from articular cartilage is mediated by the synovium and ligament after anterior cruciate ligament injury.Do gene expression changes in articular cartilage proteases of the synovial membrane correlate with expression changes of the same genes in systemic blood cells?Biomarkers of cartilage and surrounding joint tissue.Current serological possibilities for the diagnosis of arthritis with special focus on proteins and proteoglycans from the extracellular matrix.High molecular weight hyaluronic acid increases the differentiation potential of the murine chondrocytic ATDC5 cell line.Osteoarthritis in older adults.Changes in synovial fluid biochemical markers following arthroscopic surgery in patients with knee osteoarthritis.Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.Changes in serum cartilage marker levels indicate altered cartilage metabolism in families with the osteoarthritis-related type II collagen gene COL2A1 mutation.Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy?Changes in cartilage proteoglycan aggrecan after intra-articular injection of interleukin-1 in rabbits: studies of synovial fluid and articular cartilage.Effects of adenovirus-mediated bFGF, IL-1Ra and IGF-1 gene transfer on human osteoarthritic chondrocytes and osteoarthritis in rabbits.Effects of low and high dose intraarticular tiludronate on synovial fluid and clinical variables in healthy horses-a preliminary investigation.Use of synovial fluid markers of cartilage synthesis and turnover to study effects of repeated intra-articular administration of methylprednisolone acetate on articular cartilage in vivo.Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo.Antiarthritic activity of a standardized, multiherbal, Ayurvedic formulation containing Boswellia serrata: in vitro studies on knee cartilage from osteoarthritis patients.Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.Reduction in disease progression by inhibition of transforming growth factor α-CCL2 signaling in experimental posttraumatic osteoarthritis.Changes in joint cartilage aggrecan after knee injury and in osteoarthritis.Effects of a 15-month anti-TNF-α treatment on plasma levels of glycosaminoglycans in women with rheumatoid arthritis
P2860
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P2860
Changes in cartilage metabolism in arthritis are reflected by altered serum and synovial fluid levels of the cartilage proteoglycan aggrecan. Implications for pathogenesis.
description
1994 nî lūn-bûn
@nan
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Changes in cartilage metabolis ...... Implications for pathogenesis.
@ast
Changes in cartilage metabolis ...... Implications for pathogenesis.
@en
Changes in cartilage metabolis ...... Implications for pathogenesis.
@nl
type
label
Changes in cartilage metabolis ...... Implications for pathogenesis.
@ast
Changes in cartilage metabolis ...... Implications for pathogenesis.
@en
Changes in cartilage metabolis ...... Implications for pathogenesis.
@nl
prefLabel
Changes in cartilage metabolis ...... Implications for pathogenesis.
@ast
Changes in cartilage metabolis ...... Implications for pathogenesis.
@en
Changes in cartilage metabolis ...... Implications for pathogenesis.
@nl
P2093
P2860
P356
P1476
Changes in cartilage metabolis ...... Implications for pathogenesis.
@en
P2093
P2860
P356
10.1172/JCI117314
P407
P577
1994-07-01T00:00:00Z