Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.
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ANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 siteAttenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in miceDrugs in development: bisphosphonates and metalloproteinase inhibitorsRelaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explantsRepression of anti-proliferative factor Tob1 in osteoarthritic cartilageMithramycin downregulates proinflammatory cytokine-induced matrix metalloproteinase gene expression in articular chondrocytesMatrix Metalloproteinases in Non-Neoplastic Disorders.On the evolutionary relationship between chondrocytes and osteoblastsGenetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug TargetsAn overview of underlying causes and animal models for the study of age-related degenerative disorders of the spine and synovial jointsTargets, models and challenges in osteoarthritis researchOsteoarthritis pathogenesis: a review of molecular mechanismsCartilage to bone transitions in health and diseaseCheminformatics-based drug design approach for identification of inhibitors targeting the characteristic residues of MMP-13 hemopexin domainCritical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossificationPregnane X receptor knockout mice display aging-dependent wearing of articular cartilageIdentification of Targets of a New Nutritional Mixture for Osteoarthritis Management Composed by Curcuminoids Extract, Hydrolyzed Collagen and Green Tea ExtractRegulation of matrix metalloproteinase expression by dynamic tensile strain in rat fibrochondrocytesProtective effects of berberine in an experimental rat osteoarthritis modelReview of Prospects of Biological Fluid Biomarkers in Osteoarthritis.Fibronectin fragment activation of proline-rich tyrosine kinase PYK2 mediates integrin signals regulating collagenase-3 expression by human chondrocytes through a protein kinase C-dependent pathwayCaesalpinia sappan extract inhibits IL1β-mediated overexpression of matrix metalloproteinases in human chondrocytes.Inhibition of TGF-β signaling in mesenchymal stem cells of subchondral bone attenuates osteoarthritisAarhus Regenerative Orthopaedics Symposium (AROS).Effects of doxycycline on mesenchymal stem cell chondrogenesis and cartilage repair.Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis.Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.Deletion of Runx2 in Articular Chondrocytes Decelerates the Progression of DMM-Induced Osteoarthritis in Adult Mice.Clodronate exerts an anabolic effect on articular chondrocytes mediated through the purinergic receptor pathway.Targeting TGFβ signaling in subchondral bone and articular cartilage homeostasisLuteolin Inhibits the Activity, Secretion and Gene Expression of MMP-3 in Cultured Articular Chondrocytes and Production of MMP-3 in the Rat KneeADAMTS and ADAM metalloproteinases in osteoarthritis - looking beyond the 'usual suspects'.MicroRNAs and Autophagy: Fine Players in the Control of Chondrocyte Homeostatic Activities in Osteoarthritis.Effects of TLR-2/NF-κB signaling pathway on the occurrence of degenerative knee osteoarthritis: an in vivo and in vitro study.Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes.Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cdelta pathways in human adult articular chondrocytesPeriostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents.The effects of amphiregulin induced MMP-13 production in human osteoarthritis synovial fibroblast.Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis.Effect of the oral application of a highly selective MMP-13 inhibitor in three different animal models of rheumatoid arthritis.
P2860
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P2860
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Postnatal expression in hyalin ...... nduces osteoarthritis in mice.
@en
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3
@nl
type
label
Postnatal expression in hyalin ...... nduces osteoarthritis in mice.
@en
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3
@nl
prefLabel
Postnatal expression in hyalin ...... nduces osteoarthritis in mice.
@en
Postnatal expression in hyaline cartilage of constitutively active human collagenase-3
@nl
P2093
P2860
P356
P1476
Postnatal expression in hyalin ...... nduces osteoarthritis in mice.
@en
P2093
C Billinghurst
L A Neuhold
L J DeGennaro
P2860
P356
10.1172/JCI10564
P407
P577
2001-01-01T00:00:00Z