1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice - Wikidata - awgldk - TriplyDB

1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

http://www.wikidata.org/entity/Q34236794

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Neuropharmacology of New Psychoactive Substances (NPS): Focus on the Rewarding and Reinforcing Properties of Cannabimimetics and Amphetamine-Like Stimulants Spice drugs are more than harmless herbal blends: a review of the pharmacology and toxicology of synthetic cannabinoids Neurotoxicity of Synthetic Cannabinoids JWH-081 and JWH-210 Novel Drugs of Abuse: A Snapshot of an Evolving Marketplace.Development of a high-performance liquid chromatography-tandem mass spectrometry method for the identification and quantification of CP-47,497, CP-47,497-C8 and JWH-250 in mouse brain.Cross-substitution of Δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats.Diuretic effects of cannabinoids.The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.Baths salts, spice, and related designer drugs: the science behind the headlines.Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications.Inhalation exposure to smoke from synthetic "marijuana" produces potent cannabimimetic effects in mice The Changing Face of Recreational Drug Use.The Directive 2010/63/EU on animal experimentation may skew the conclusions of pharmacological and behavioural studies.Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.A major glucuronidated metabolite of JWH-018 is a neutral antagonist at CB1 receptors.In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA.Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids.Synthetic Pot: Not Your Grandfather's Marijuana.Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs.Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids.Identification of MDMB-FUBINACA in commercially available e-liquid formulations sold for use in electronic cigarettes.Qualitative Analysis and Detection of the Pyrolytic Products of JWH-018 and 11 Additional Synthetic Cannabinoids in the Presence of Common Herbal Smoking Substrates.Acute and residual effects in adolescent rats resulting from exposure to the novel synthetic cannabinoids AB-PINACA and AB-FUBINACA.Neurocognition and subjective experience following acute doses of the synthetic cannabinoid JWH-018: a phase 1, placebo-controlled, pilot study.Apparent Affinity Estimates and Reversal of the Effects of Synthetic Cannabinoids AM-2201, CP-47,497, JWH-122, and JWH-250 by Rimonabant in Rhesus Monkeys.Behavioral responses to acute and sub-chronic administration of the synthetic cannabinoid JWH-018 in adult mice prenatally exposed to corticosterone.Driving under the influence of synthetic cannabinoids ("Spice"): a case series.Repeated Exposure to the "Spice" Cannabinoid JWH-018 Induces Tolerance and Enhances Responsiveness to 5-HT1A Receptor Stimulation in Male Rats.Synthetic cannabinoids found in "spice" products alter body temperature and cardiovascular parameters in conscious male rats.Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ-THC Behavioral and Pharmacokinetic Profile of Indole-Derived Synthetic Cannabinoids JWH-073 and JWH-210 as Compared to the Phytocannabinoid Δ-THC in Rats

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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2011 nî lūn-bûn

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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2011 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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J.DRUGALCDEP.2011.11.001

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Drug and Alcohol Dependence

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1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice

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Jenny L Wiley

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Julie A Marusich

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P2860

Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity

Cannabinergic aminoalkylindoles, including AM678=JWH018 found in 'Spice', examined using drug (Δ(9)-tetrahydrocannabinol) discrimination for rats

Withdrawal phenomena and dependence syndrome after the consumption of "spice gold"

Aminoalkylindole analogs: cannabimimetic activity of a class of compounds structurally distinct from delta 9-tetrahydrocannabinol

Conformationally restrained analogues of pravadoline: nanomolar potent, enantioselective, (aminoalkyl)indole agonists of the cannabinoid receptor

Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents.

Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists.

Recent developments in the medicinal chemistry of cannabimimetic indoles, pyrroles and indenes.

CB2 receptor ligands.

JWH018, a common constituent of 'Spice' herbal blends, is a potent and efficacious cannabinoid CB receptor agonist

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John W. Huffman

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