Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression - Wikidata - awgldk - TriplyDB

Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression

Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression

http://www.wikidata.org/entity/Q34240499

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Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune Response Programmed cell death protein-1/programmed cell death ligand-1 pathway inhibition and predictive biomarkers: understanding transforming growth factor-beta role Targeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor Immunity Molecular and cellular insights into T cell exhaustion The role of transforming growth factor β1 in the regulation of blood pressure A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells Transforming growth factor β as regulator of cancer stemness and metastasis Immunological parameters as a new lead in the diagnosis of ovarian cancer.The significance of FOXP1 in diffuse large B-cell lymphoma.Size does not matter: commensal microorganisms forge tumor-promoting inflammation and anti-tumor immunity.Molecular profiling of CD8 T cells in autochthonous melanoma identifies Maf as driver of exhaustion.Ubiquitin-like Molecule ISG15 Acts as an Immune Adjuvant to Enhance Antigen-specific CD8 T-cell Tumor Immunity.Transforming growth factor-β1 and diabetic nephropathy IL15 Agonists Overcome the Immunosuppressive Effects of MEK Inhibitors.Naïve CD8(+) T cell derived tumor-specific cytotoxic effectors as a potential remedy for overcoming TGF-β immunosuppression in the tumor microenvironment Transforming growth factor beta1 and aldosterone.The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases.Transforming growth factor-β1 regulates the nascent hematopoietic stem cell niche by promoting gluconeogenesis.FOXP1 is a regulator of quiescence in healthy human CD4+ T cells and is constitutively repressed in T cells from patients with lymphoproliferative disorders.Trametinib Drives T-cell-Dependent Control of KRAS-Mutated Tumors by Inhibiting Pathological Myelopoiesis Molecular Profile of Tumor-Specific CD8+ T Cell Hypofunction in a Transplantable Murine Cancer Model.Anaerobic Bacterial Fermentation Products Increase Tuberculosis Risk in Antiretroviral-Drug-Treated HIV Patients.Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells.Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies.Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors.Suppression of FIP200 and autophagy by tumor-derived lactate promotes naïve T cell apoptosis and affects tumor immunity.Tumor Cell-Independent Estrogen Signaling Drives Disease Progression through Mobilization of Myeloid-Derived Suppressor Cells.Resistance to TGFβ suppression and improved anti-tumor responses in CD8+ T cells lacking PTPN22.NFAT5-Regulated Macrophage Polarization Supports the Proinflammatory Function of Macrophages and T Lymphocytes.Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells.Frontline Science: Microbiota reconstitution restores intestinal integrity after cisplatin therapy.TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer.The transcription factor Foxp1 preserves integrity of an active Foxp3 locus in extrathymic Treg cells

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Transforming growth factor β-mediated suppression of antitumor T cells requires FoxP1 transcription factor expression

http://www.wikidata.org/entity/Q34240499

description

2014 nî lūn-bûn

@nan

2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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Transforming growth factor β-m ...... ranscription factor expression

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J.IMMUNI.2014.08.012

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Transforming growth factor β-m ...... ranscription factor expression

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Amelia J Tesone

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Fahmida Sarmin

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Jenny M Nguyen

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Jose R Conejo-Garcia

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Julia Tchou

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Mark E Borowsky

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Melanie R Rutkowski

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Michael J Allegrezza

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Nikolaos Svoronos

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Tom L Stephen

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P2860

Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

BATF-JUN is critical for IRF4-mediated transcription in T cells

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

Immunosuppressive networks in the tumour environment and their therapeutic relevance

Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer

T cell exhaustion

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo.

Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer.

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427-439

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10.1016/J.IMMUNI.2014.08.012

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3

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41

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Alfredo Perales-Puchalt

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2014-09-01T00:00:00Z

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265859202

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25238097

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4174366

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