iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
about
Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosaPhosphatidylserine exposure is required for ADAM17 sheddase functionLarge Lateral Movement of Transmembrane Helix S5 Is Not Required for Substrate Access to the Active Site of Rhomboid Intramembrane ProteaseRhomboids, signalling and cell biologyCellular and molecular regulation of innate inflammatory responsesRegulation of tumour necrosis factor signalling: live or let dieHaploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligasesRhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationStructure and mechanism of rhomboid proteaseEctodomain Shedding by ADAM17: Its Role in Neutrophil Recruitment and the Impairment of This Process during SepsisRHBDD1 upregulates EGFR via the AP-1 pathway in colorectal cancer.Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signalingiRHOM2-dependent regulation of ADAM17 in cutaneous disease and epidermal barrier functionActivated CD8+ T cells induce expansion of Vβ5+ regulatory T cells via TNFR2 signaling.Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACENetwork dynamics determine the autocrine and paracrine signaling functions of TNF.iRhom2 is required for the secretion of mouse TNFαIRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking.Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivoTACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.Differential surface expression of ADAM10 and ADAM17 on human T lymphocytes and tumor cells.Proteomic analysis of differentially expressed skin proteins in iRhom2(Uncv) miceThe cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.iRhom2 mutation leads to aberrant hair follicle differentiation in mice.Soluble interleukin-15 complexes are generated in vivo by type I interferon dependent and independent pathwaysThe Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingiRhom1 regulates proteasome activity via PAC1/2 under ER stressRhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway.Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17.A role for cGMP in inducible nitric-oxide synthase (iNOS)-induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes.Involvement of Toso in activation of monocytes, macrophages, and granulocytesiRhoms; Its Functions and Essential Roles.Reactive oxygen species delay control of lymphocytic choriomeningitis virusTIMP3 Modulates GHR Abundance and GH SensitivityRhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα
P2860
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P2860
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@ast
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@en
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@nl
type
label
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@ast
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@en
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@nl
prefLabel
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@ast
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@en
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@nl
P2093
P2860
P50
P921
P356
P1433
P1476
iRhom2 regulation of TACE cont ...... Listeria and responses to LPS
@en
P2093
Aditya Murthy
Andrew Wakeham
Annick Itie-Youten
Carl P Blobel
David R McIlwain
Gordon Duncan
Haifeng C Xu
Karl S Lang
Kazuhito Ohishi
Koichi Hamada
P2860
P304
P356
10.1126/SCIENCE.1214448
P407
P577
2012-01-01T00:00:00Z