Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis - Wikidata - awgldk - TriplyDB

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

http://www.wikidata.org/entity/Q34247703

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TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathway The Rationale for Insulin Therapy in Alzheimer's Disease Metabolic regulation of T cell differentiation and function Nutrition facts in multiple sclerosis Integrating canonical and metabolic signalling programmes in the regulation of T cell responses Multiple sclerosis: molecular mechanisms and therapeutic opportunities Metabolic reprogramming in macrophages and dendritic cells in innate immunity Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease Role of platelets in neuroinflammation: a wide-angle perspective Metformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female mice Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity AMPK activation--protean potential for boosting healthspan.Protective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion.Novel synthetic small-molecule activators of AMPK as enhancers of autophagy and amyloid-β peptide degradation.Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease.Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.Metformin limits the adipocyte tumor-promoting effect on ovarian cancer.Metformin attenuates experimental autoimmune arthritis through reciprocal regulation of Th17/Treg balance and osteoclastogenesis.Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase.Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity.Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice T regulatory lymphocytes and endothelial function in pediatric obstructive sleep apnea AMP-activated protein kinase suppresses matrix metalloproteinase-9 expression in mouse embryonic fibroblasts.Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice.Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis.Metabolic reprograming of mononuclear phagocytes in progressive multiple sclerosis.Loss of AMP-activated protein kinase induces mitochondrial dysfunction and proinflammatory response in unstimulated Abcd1-knockout mice mixed glial cells.Resveratrol activates AMPK and suppresses LPS-induced NF-κB-dependent COX-2 activation in RAW 264.7 macrophage cells.Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.The brighter (and evolutionarily older) face of the metabolic syndrome: evidence from Trypanosoma cruzi infection in CD-1 mice Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response Regulation and function of mTOR signalling in T cell fate decisions.Untargeted Plasma Metabolomics Identifies Endogenous Metabolite with Drug-like Properties in Chronic Animal Model of Multiple Sclerosis Diabetes medications: Impact on inflammation and wound healing A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms.AMP-activated protein kinase signaling protects oligodendrocytes that restore central nervous system functions in an experimental autoimmune encephalomyelitis model.AMP-activated protein kinase restricts IFN-γ signaling.

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Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

http://www.wikidata.org/entity/Q34247703

description

2009 nî lūn-bûn

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2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2009 թվականի հունիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Journal of Immunology

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Metformin attenuated the autoi ...... l models of multiple sclerosis

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Inderjit Singh

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Manjeet K Paintlia

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Md Nasrul Hoda

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Musfiquidin Khan

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Narender Nath

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Shailendra Giri

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P2860

Role of AMP-activated protein kinase in mechanism of metformin action

Transforming growth factor-beta induces development of the T(H)17 lineage

Expression of immunologically relevant endothelial cell activation antigens on isolated central nervous system microvessels from patients with multiple sclerosis

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Adhesion molecule expression and regulation on cells of the central nervous system.

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19494326

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multiple sclerosis

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