Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus
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Control of the thymic medulla and its influence on αβT-cell developmentRole of Dendritic Cells in the Induction of Lymphocyte ToleranceThe Contribution of Chemokines and Migration to the Induction of Central Tolerance in the ThymusExosomes in the Thymus: Antigen Transfer and VesiclesThymic Crosstalk Coordinates Medulla Organization and T-Cell Tolerance InductionMolecular mechanism and cellular function of MHCII ubiquitinationPromiscuous Gene Expression in the Thymus: A Matter of Epigenetics, miRNA, and More?CCR4 promotes medullary entry and thymocyte-dendritic cell interactions required for central tolerance.Friend or foe: the dichotomous impact of T cells on neuro-de/re-generation during agingRoles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance inductionUnique properties of thymic antigen-presenting cells promote epigenetic imprinting of alloantigen-specific regulatory T cells.Immunomodulatory Functions of BTLA and HVEM Govern Induction of Extrathymic Regulatory T Cells and Tolerance by Dendritic Cells.Medullary thymic epithelial cells and central tolerance in autoimmune hepatitis development: novel perspective from a new mouse model.Tolerance: AIREs and graces.Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.Regulatory T cell identity: formation and maintenanceThymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation.The Role of Dendritic Cells in Central ToleranceT cells in the control of organ-specific autoimmunitymTORC1 in Thymic Epithelial Cells Is Critical for Thymopoiesis, T-Cell Generation, and Temporal Control of γδT17 Development and TCRγ/δ RecombinationPak2 Links TCR Signaling Strength to the Development of Regulatory T Cells and Maintains Peripheral ToleranceBrd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cellsIntercellular Protein Transfer from Thymocytes to Thymic Epithelial CellsNatural Th17 cells are critically regulated by functional medullary thymic microenvironments.Central tolerance to self revealed by the autoimmune regulator.CD4+ T Cell Tolerance to Tissue-Restricted Self Antigens Is Mediated by Antigen-Specific Regulatory T Cells Rather Than Deletion.Single-cell transcriptome analysis reveals coordinated ectopic gene-expression patterns in medullary thymic epithelial cellsImmune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance.Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus.Absence of MHC class II on cDCs results in microbial-dependent intestinal inflammationDendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells.mTORC2 in Thymic Epithelial Cells Controls Thymopoiesis and T Cell Development.Deletional tolerance prevents AQP4-directed autoimmunity in mice.Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: what we learn from intrathymic migration.The contribution of NF-κB signalling to immune regulation and tolerance.Thymic stromal cell subsets for T cell development.AIRE expands: new roles in immune tolerance and beyond.Autoimmune regulator and self-tolerance - molecular and clinical aspects.Development of T-cell tolerance utilizes both cell-autonomous and cooperative presentation of self-antigen.How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity.
P2860
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P2860
Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus
description
2014 nî lūn-bûn
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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Distinct contributions of Aire ...... f self-tolerance in the thymus
@ast
Distinct contributions of Aire ...... f self-tolerance in the thymus
@en
Distinct contributions of Aire ...... f self-tolerance in the thymus
@nl
type
label
Distinct contributions of Aire ...... f self-tolerance in the thymus
@ast
Distinct contributions of Aire ...... f self-tolerance in the thymus
@en
Distinct contributions of Aire ...... f self-tolerance in the thymus
@nl
prefLabel
Distinct contributions of Aire ...... f self-tolerance in the thymus
@ast
Distinct contributions of Aire ...... f self-tolerance in the thymus
@en
Distinct contributions of Aire ...... f self-tolerance in the thymus
@nl
P2093
P2860
P50
P1433
P1476
Distinct contributions of Aire ...... f self-tolerance in the thymus
@en
P2093
Jeffrey I Gordon
Justin S A Perry
Katherine Nutsch
Kenneth M Murphy
P2860
P304
P356
10.1016/J.IMMUNI.2014.08.007
P407
P577
2014-09-11T00:00:00Z