Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds
about
Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasitesHistone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humansProfiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasitesIdentification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4md00274a.Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available: SuppleHistone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity.
P2860
Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Development of diaminoquinazol ...... d-stage antimalarial compounds
@ast
Development of diaminoquinazol ...... d-stage antimalarial compounds
@en
Development of diaminoquinazol ...... d-stage antimalarial compounds
@nl
type
label
Development of diaminoquinazol ...... d-stage antimalarial compounds
@ast
Development of diaminoquinazol ...... d-stage antimalarial compounds
@en
Development of diaminoquinazol ...... d-stage antimalarial compounds
@nl
prefLabel
Development of diaminoquinazol ...... d-stage antimalarial compounds
@ast
Development of diaminoquinazol ...... d-stage antimalarial compounds
@en
Development of diaminoquinazol ...... d-stage antimalarial compounds
@nl
P2093
P2860
P50
P356
P1433
P1476
Development of diaminoquinazol ...... d-stage antimalarial compounds
@en
P2093
Artur Scherf
Joachim Caron
Nitipol Srimongkolpithak
Scott Blundell
P2860
P304
P356
10.1002/CMDC.201402098
P577
2014-07-09T00:00:00Z