Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin.

Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin.

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http://www.wikidata.org/entity/Q34255016

Q34255016

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The links between insulin resistance, diabetes, and cancer Dietary and pharmacological modification of the insulin/IGF-1 system: exploiting the full repertoire against cancer 2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications Lipid Signaling in Tumorigenesis.DAG/PKCδ and IP3/Ca²⁺/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway.Oxidative stress mediates the disruption of airway epithelial tight junctions through a TRPM2-PLCγ1-PKCα signaling pathway.Lentivirus-mediated PLCγ1 gene short-hairpin RNA suppresses tumor growth and metastasis of human gastric adenocarcinoma.High glucose modulates antiproliferative effect and cytotoxicity of 5-fluorouracil in human colon cancer cells.Continuous or Transient High Level of Glucose Exposure Differentially Increases Coronary Artery Endothelial Cell Proliferation and Human Colon Cancer Cell Proliferation.Membrane-tethered AKT kinase regulates basal synaptic transmission and early phase LTP expression by modulation of post-synaptic AMPA receptor level.Phosphoinositide-specific phospholipase Cγ1 inhibition induces autophagy in human colon cancer and hepatocellular carcinoma cells.Kinesin family member 11 contributes to the progression and prognosis of human breast cancer.Oncogenic activity of insulin in the development of non-small cell lung carcinoma.Phospholipase Cγ1 links inflammation and tumorigenesis in colitis-associated cancer.High glucose and insulin enhance uPA expression, ROS formation and invasiveness in breast cancer-derived cells.Rosiglitazone diminishes the high-glucose-induced modulation of 5-fluorouracil cytotoxicity in colorectal cancer cells.High glucose induces epithelial-mesenchymal transition and results in the migration and invasion of colorectal cancer cells.Dendrobium mixture regulates hepatic gluconeogenesis in diabetic rats via the phosphoinositide-3-kinase/protein kinase B signaling pathway.

P2860

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P2860

Akt and phospholipase Cγ are involved in the regulation of growth and migration of MDA-MB-468 breast cancer and SW480 colon cancer cells when cultured with diabetogenic levels of glucose and insulin.

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http://www.wikidata.org/entity/Q34255016

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2012年の論文

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