First-pass elimination. Basic concepts and clinical consequences.
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Representative Sinusoids for Hepatic Four-Scale Pharmacokinetics SimulationsPrinciples of pharmacotherapy: II. Pharmacokineticsκ Agonists as a novel therapy for menopausal hot flashes.A patchless dissolving microneedle delivery system enabling rapid and efficient transdermal drug delivery.Glucose-dependent regulation of pregnane X receptor is modulated by AMP-activated protein kinase.Optimization of intestinal microsomal preparation in the rat: A systematic approach to assess the influence of various methodologies on metabolic activity and scaling factors.An enhancer-blocking element regulates the cell-specific expression of alcohol dehydrogenase 7.Pharmacokinetics of felodipine after intravenous and chronic oral administration in patients with congestive heart failureSelective targeting of liver cancer with the endothelial marker CD146.The microbial pharmacists within us: a metagenomic view of xenobiotic metabolismTargeted delivery of liquid microvolumes into the lung.Gene regulation by dietary microRNAs.Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions.Intestinal UGTs as potential modifiers of pharmacokinetics and biological responses to drugs and xenobiotics.The peptide-based thrombin inhibitor CRC 220 is a new substrate of the basolateral rat liver organic anion-transporting polypeptide.Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans.Medical Comorbidity and Complications.Nanovehicular intracellular delivery systems.Management of opioid analgesic overdoseOral anticancer drugs: mechanisms of low bioavailability and strategies for improvement.Basics and recent advances in peptide and protein drug delivery.Nutrition, microRNAs, and Human Health.Drug absorption.Prediction of human pharmacokinetics--evaluation of methods for prediction of hepatic metabolic clearance.The clinical implications of first-pass metabolism: treatment strategies for the 1990s.A nonlinear physiologic pharmacokinetic model: I. Steady-state.Milk exosomes: beyond dietary microRNAs.Effect of chronic bile duct obstruction and LPS upon targeting of naproxen to the liver using naproxen-albumin conjugate.In vivo effects of synthetic cannabinoids JWH-018 and JWH-073 and phytocannabinoid Δ9-THC in mice: inhalation versus intraperitoneal injection.Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation.Triazolam kinetics: interaction with cimetidine, propranolol, and the combination.Bioreversible derivatives of phenol. 2. Reactivity of carbonate esters with fatty acid-like structures towards hydrolysis in aqueous solutions.Bioreversible derivatives of phenol. 1. The role of human serum albumin as related to the stability and binding properties of carbonate esters with fatty acid-like structures in aqueous solution and biological media.Rapid fabrication method of a microneedle mold with controllable needle height and width.Specific packaging and circulation of cytochromes P450, especially 2E1 isozyme, in human plasma exosomes and their implications in cellular communications.Impact of novel N-aryl piperamide NO donors on NF-κB translocation in neuroinflammation: rational drug-designing synthesis and biological evaluation.Captopril methylation in human liver and kidney: interindividual variability.Pharmacokinetics and kinetic-dynamic modelling of aminophenones as methaemoglobin formers.A model of blood-ammonia homeostasis based on a quantitative analysis of nitrogen metabolism in the multiple organs involved in the production, catabolism, and excretion of ammonia in humans.Evaluation of a Pretargeting Strategy for Molecular Imaging of the Prostate Stem Cell Antigen with a Single Chain Antibody.
P2860
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P2860
First-pass elimination. Basic concepts and clinical consequences.
description
1984 nî lūn-bûn
@nan
1984 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
First-pass elimination. Basic concepts and clinical consequences.
@ast
First-pass elimination. Basic concepts and clinical consequences.
@en
First-pass elimination. Basic concepts and clinical consequences.
@nl
type
label
First-pass elimination. Basic concepts and clinical consequences.
@ast
First-pass elimination. Basic concepts and clinical consequences.
@en
First-pass elimination. Basic concepts and clinical consequences.
@nl
prefLabel
First-pass elimination. Basic concepts and clinical consequences.
@ast
First-pass elimination. Basic concepts and clinical consequences.
@en
First-pass elimination. Basic concepts and clinical consequences.
@nl
P1476
First-pass elimination. Basic concepts and clinical consequences.
@en
P2093
P356
10.2165/00003088-198409010-00001
P577
1984-01-01T00:00:00Z
P6179
1025612113