The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins.
about
Defining the role of the Bcl-2 family proteins in Huntington's diseaseInteractive HIV-1 Tat and morphine-induced synaptodendritic injury is triggered through focal disruptions in Na⁺ influx, mitochondrial instability, and Ca²⁺ overload.From pathways to targets: understanding the mechanisms behind polyglutamine disease.Pridopidine, a dopamine stabilizer, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.Pridopidine selectively occupies sigma-1 rather than dopamine D2 receptors at behaviorally active doses.Tolerability and efficacy of the monoaminergic stabilizer (-)-OSU6162 (PNU-96391A) in Huntington's disease: a double-blind cross-over study.
P2860
The dopaminergic stabilizer, (-)-OSU6162, rescues striatal neurons with normal and expanded polyglutamine chains in huntingtin protein from exposure to free radicals and mitochondrial toxins.
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@ast
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@en
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@nl
type
label
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@ast
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@en
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@nl
prefLabel
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@ast
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@en
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@nl
P2093
P1433
P1476
The dopaminergic stabilizer, ( ...... cals and mitochondrial toxins.
@en
P2093
J G de Yebenes
M J Casarejos
M Puigdellivol
P304
P356
10.1016/J.BRAINRES.2012.04.021
P407
P577
2012-04-21T00:00:00Z