Pridopidine, a dopamine stabilizer, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.
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The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington diseaseSigma-1 (σ1) Receptor in Memory and Neurodegenerative Diseases.Profile of pridopidine and its potential in the treatment of Huntington disease: the evidence to date.Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases.Resting-state connectivity and modulated somatomotor and default-mode networks in Huntington disease.Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice.Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease.Pridopidine Reverses Phencyclidine-Induced Memory Impairment.Pridopidine: Overview of Pharmacology and Rationale for its Use in Huntington's Disease.Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse.
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P2860
Pridopidine, a dopamine stabilizer, improves motor performance and shows neuroprotective effects in Huntington disease R6/2 mouse model.
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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name
Pridopidine, a dopamine stabil ...... gton disease R6/2 mouse model.
@en
type
label
Pridopidine, a dopamine stabil ...... gton disease R6/2 mouse model.
@en
prefLabel
Pridopidine, a dopamine stabil ...... gton disease R6/2 mouse model.
@en
P2860
P50
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P1476
Pridopidine, a dopamine stabil ...... gton disease R6/2 mouse model.
@en
P2093
Luigi Frati
Mariagrazia Favellato
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P304
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10.1111/JCMM.12604
P577
2015-06-22T00:00:00Z