Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models - Wikidata - awgldk - TriplyDB

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

http://www.wikidata.org/entity/Q34260011

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A polycystin-centric view of cyst formation and disease: the polycystins revisited OFD1 and flotillins are integral components of a ciliary signaling protein complex organized by polycystins in renal epithelia and odontoblasts New insights into an old organelle: meeting report on biology of cilia and flagella Unique spatiotemporal requirements for intraflagellar transport genes during forebrain development.A tissue-specific role for intraflagellar transport genes during craniofacial development.Dysfunction of intraflagellar transport-A causes hyperphagia-induced obesity and metabolic syndrome.Heterotrimeric G protein signaling in polycystic kidney disease High-resolution genetic localization of a modifying locus affecting disease severity in the juvenile cystic kidneys (jck) mouse model of polycystic kidney disease Six2creFrs2α knockout mice are a novel model of renal cystogenesis.Developmental signaling: does it bridge the gap between cilia dysfunction and renal cystogenesis?Cilia-dependent GLI processing in neural crest cells is required for tongue development.Primary Cilia in Cystic Kidney Disease.Ectopic Phosphorylated Creb Marks Dedifferentiated Proximal Tubules in Cystic Kidney Disease.Many Genes-One Disease? Genetics of Nephronophthisis (NPHP) and NPHP-Associated Disorders.Aberrant Regulation of Notch3 Signaling Pathway in Polycystic Kidney Disease.Ciliary Mechanisms of Cyst Formation in Polycystic Kidney Disease.Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8.Ttc21b Is Required in Bergmann Glia for Proper Granule Cell Radial Migration.[Cilia and renal cysts].

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P2860

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

http://www.wikidata.org/entity/Q34260011

description

2014 nî lūn-bûn

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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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type

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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prefLabel

Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

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Journal of the American Society of Nephrology

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Downregulating hedgehog signaling reduces renal cystogenic potential of mouse models

@en

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Anindita Chatterjee

http://www.w3.org/2001/XMLSchema#string

Annick Turbe-Doan

http://www.w3.org/2001/XMLSchema#string

Bailey A Allard

http://www.w3.org/2001/XMLSchema#string

Damon T Jacobs

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David R Beier

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George C Talbott

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Luciane M Silva

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Mary Prysak

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Michael P Schonfeld

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Pamela V Tran

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P2860

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb

NEK8 mutations affect ciliary and centrosomal localization and may cause nephronophthisis

Vertebrate Smoothened functions at the primary cilium.

Mechanisms and functions of Hedgehog signalling across the metazoa

Cilia and developmental signaling

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia

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2201-2212

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10.1681/ASN.2013070735

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10

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25

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2014-04-03T00:00:00Z

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261374996

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24700869

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4178433

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