A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage - Wikidata - awgldk - TriplyDB

A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

http://www.wikidata.org/entity/Q34260391

about

Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication XRCC1 is specifically associated with poly(ADP-ribose) polymerase and negatively regulates its activity following DNA damage Poly(ADP-ribose) polymerase (PARP-1) has a controlling role in homologous recombination ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death Structure of the catalytic fragment of poly(AD-ribose) polymerase from chicken DNA excision repair and DNA damage-induced apoptosis are linked to Poly(ADP-ribosyl)ation but have different requirements for p53 Specific interaction of DNA polymerase beta and DNA ligase I in a multiprotein base excision repair complex from bovine testis Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions Poly(ADP-ribose) polymerase-1 and its cleavage products differentially modulate cellular protection through NF-kappaB-dependent signaling Poly(ADP-ribose) polymerase in DNA damage-response pathway: implications for radiation oncology.Sensing DNA damage by PARP-like fingers.A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription.Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy.DNA repair defect in poly(ADP-ribose) polymerase-deficient cell lines.Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence.Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes.Efficient retroviral infection of mammalian cells is blocked by inhibition of poly(ADP-ribose) polymerase activity Hypersensitivity phenotypes associated with genetic and synthetic inhibitor-induced base excision repair deficiency New opportunities in chemosensitization and radiosensitization: modulating the DNA-damage response.Poly(ADP-ribosylation) and genomic stability.Poly(ADP-ribosyl)ation in mammalian ageing.Proteolysis and the biochemistry of life-or-death decisions.Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes.Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA.Crosstalk between poly(ADP-ribose) polymerase and sirtuin enzymes.Structural recognition of DNA by poly(ADP-ribose)polymerase-like zinc finger families.Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines.Inhibition of the activity of poly (ADP-ribose) polymerase reduces heart ischaemia/reperfusion injury via suppressing JNK-mediated AIF translocation.Poly ADP-ribose polymerase-1 and health.Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells.Role of PARP-1 in prostate cancer.Response of Dictyostelium discoideum to UV-C and involvement of poly (ADP-ribose) polymerase.Coordination of DNA single strand break repair.Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis.Activation and caspase-mediated inhibition of PARP: a molecular switch between fibroblast necrosis and apoptosis in death receptor signaling.Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1.

P2860

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P2860

A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

http://www.wikidata.org/entity/Q34260391

description

1995 nî lūn-bûn

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1995 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1995 թվականի մայիսին հրատարակված գիտական հոդված

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1995年の論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年論文

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1995年论文

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name

A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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A dominant-negative mutant of ...... exchange following DNA damage

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P2093

De Murcia G

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De Murcia JM

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Gowans B

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Grunwald D

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Hunting D

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Trucco C

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P2860

Effects of UV, 4-NQO and TPA on gene expression in cultured human epidermal keratinocytes

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

Selective extraction of polyoma DNA from infected mouse cell cultures

Participation of p53 protein in the cellular response to DNA damage

Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain in mammalian cells.

Poly(ADP-ribose) polymerase auto-modification and interaction with DNA: electron microscopic visualization.

The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity.

Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells

Poly(ADP-ribose) polymerase stimulates DNA polymerase alpha by physical association.

Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line.

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4753-4757

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11

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92

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15438588

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7761396

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41785

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