Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects.
about
Quantification of the glycogen cascade system: the ultrasensitive responses of liver glycogen synthase and muscle phosphorylase are due to distinctive regulatory designs.Ultrasensitivity in the mitogen-activated protein kinase cascadeProtein sequestration generates a flexible ultrasensitive response in a genetic networkThreshold responses to morphogen gradients by zero-order ultrasensitivityMolecular signaling network motifs provide a mechanistic basis for cellular threshold responsesComposite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligaseRobustness in glyoxylate bypass regulationHigh-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networksRoles of protein ubiquitination and degradation kinetics in biological oscillationsCompact modeling of allosteric multisite proteins: application to a cell size checkpointA systems model of phosphorylation for inflammatory signaling eventsRescaling of Spatio-Temporal Sensing in Eukaryotic ChemotaxisA Compartmentalized Out-of-Equilibrium Enzymatic Reaction Network for Sustained Autonomous Movement.Exploiting the dynamic properties of covalent modification cycle for the design of synthetic analog biomolecular circuitryDefining network topologies that can achieve biochemical adaptation.Ultrasensitive response motifs: basic amplifiers in molecular signalling networks.Nitrogen assimilation in Escherichia coli: putting molecular data into a systems perspectiveTranscriptional dynamics of the embryonic stem cell switch.Control of canalization and evolvability by Hsp90Enzyme localization can drastically affect signal amplification in signal transduction pathways.Dissecting microregulation of a master regulatory network.Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataComputational modeling of the hematopoietic erythroid-myeloid switch reveals insights into cooperativity, priming, and irreversibilityBuilding biological memory by linking positive feedback loops.A Clb/Cdk1-mediated regulation of Fkh2 synchronizes CLB expression in the budding yeast cell cycle.Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation.The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transductionNegative auto-regulation increases the input dynamic-range of the arabinose system of Escherichia coliProduct dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascadesInferring Biological Mechanisms by Data-Based Mathematical Modelling: Compartment-Specific Gene Activation during Sporulation in Bacillus subtilis as a Test Case.Self-organization of polarized cell signaling via autocrine circuits: computational model analysis.Modeling Dose-response at Low Dose: A Systems Biology Approach for Ionization RadiationUltrasensitivity part I: Michaelian responses and zero-order ultrasensitivity.Triggering the all-or-nothing switch into mitosis.MAP kinase modules: the excursion model and the steps that count.The Zds proteins control entry into mitosis and target protein phosphatase 2A to the Cdc25 phosphatase.Bistable responses in bacterial genetic networks: designs and dynamical consequencesA phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast.Genetic control of morphogenesis in Dictyostelium.Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties.
P2860
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P2860
Ultrasensitivity in biochemical systems controlled by covalent modification. Interplay between zero-order and multistep effects.
description
1984 nî lūn-bûn
@nan
1984 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1984 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
name
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@ast
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@en
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@nl
type
label
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@ast
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@en
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@nl
prefLabel
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@ast
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@en
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@nl
P1476
Ultrasensitivity in biochemica ...... o-order and multistep effects.
@en
P2093
Goldbeter A
Koshland DE Jr
P304
14441-14447
P407
P577
1984-12-01T00:00:00Z