The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
about
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemiaConsistent loss of heterozygosity at 14Q32 in lymphoid blast crisis of chronic myeloid leukemia.NUP98 gene rearrangements and the clonal evolution of chronic myelogenous leukemia.C/EBPdelta expression in a BCR-ABL-positive cell line induces growth arrest and myeloid differentiation.Chronic myelogenous leukemia as a paradigm of early cancer and possible curative strategies.Molecular mechanisms in the evolution of chronic myelocytic leukemia.Apoptosis as a tool for therapeutic agents in haematological diseases.Mutation of the endogenous p53 gene in cells transformed by HPV-16 E7 and EJ c-ras confers a growth advantage involving an autocrine mechanism.Restoration of C/EBPalpha expression in a BCR-ABL+ cell line induces terminal granulocytic differentiation.Expression of the DCC gene in human hematological malignancies.Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation.c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells.Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance.P53 gene mutations in lymphoid diseases and their possible relevance to drug resistance.The SKM-1 leukemic cell line established from a patient with progression to myelomonocytic leukemia in myelodysplastic syndrome (MDS)-contribution to better understanding of MDS.Expression of the PAX5/BSAP transcription factor in haematological tumour cells and further molecular characterization of the t(9;14)(p13;q32) translocation in B-cell non-Hodgkin's lymphoma.p53: guardian of cellular senescence.Establishment and characterization of a new Ph1-positive chronic myeloid leukemia cell line MC3 with trilineage phenotype and an altered p53 gene.p53 mutations, methylation and genomic instability in the progression of chronic myeloid leukaemia.Chronic myelogenous leukemia molecular signature.Pooled analysis of p53 mutations in hematological malignancies.Apoptosis in chronic myelogenous leukemia: studies of stage-specific differences.Double P53 point mutation in extramedullary blast crisis of chronic myelogenous leukemia.Structural organization of BCR-ABL gene in chronic phase and blast transformation in chronic myeloid leukemia patients.
P2860
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P2860
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
description
1991 nî lūn-bûn
@nan
1991 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@ast
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@en
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@nl
type
label
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@ast
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@en
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@nl
prefLabel
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@ast
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@en
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@nl
P2093
P2860
P356
P1476
The spectrum of molecular alterations in the evolution of chronic myelocytic leukemia.
@en
P2093
P2860
P304
P356
10.1172/JCI115234
P407
P577
1991-06-01T00:00:00Z