Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance.
about
SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations.The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeatsLoss of p53 impedes the antileukemic response to BCR-ABL inhibitionBcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation.c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells.Comparative genomic hybridization reveals previously undescribed amplifications and deletions in the chronic myeloid leukemia-derived K-562 cell line.
P2860
Chromosome 17 abnormalities and inactivation of the p53 gene in chronic myeloid leukemia and their prognostic significance.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Chromosome 17 abnormalities an ...... their prognostic significance.
@en
type
label
Chromosome 17 abnormalities an ...... their prognostic significance.
@en
prefLabel
Chromosome 17 abnormalities an ...... their prognostic significance.
@en
P2860
P1433
P1476
Chromosome 17 abnormalities an ...... their prognostic significance.
@en
P2093
P2860
P304
P356
10.3109/10428199509107891
P577
1995-10-01T00:00:00Z