The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor - Wikidata - awgldk - TriplyDB

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

http://www.wikidata.org/entity/Q34264864

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Wnt signaling in cancer stem cells and colon cancer metastasis Colorectal cancer models for novel drug discovery Understanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversies Microenvironmental control of stem cell fate in intestinal homeostasis and disease Defining hierarchies of stemness in the intestine: evidence from biomarkers and regulatory pathways Chemopreventive drugs: mechanisms via inhibition of cancer stem cells in colorectal cancer Paneth cells in intestinal homeostasis and tissue injury In vivo analysis of Lrig genes reveals redundant and independent functions in the inner ear Identification of quiescent, stem-like cells in the distal female reproductive tract Current understanding concerning intestinal stem cells Stem cell dynamics and pretumor progression in the intestinal tract Use of Cancer Stem Cells to Investigate the Pathogenesis of Colitis-associated Cancer Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging.Lrig2-deficient mice are protected against PDGFB-induced glioma A calibrated agent-based computer model of stochastic cell dynamics in normal human colon crypts useful for in silico experiments.Pathobiology of Helicobacter pylori-Induced Gastric Cancer.Unraveling intestinal stem cell behavior with models of crypt dynamics A central role for vesicle trafficking in epithelial neoplasia: intracellular highways to carcinogenesis.Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse Models.Notch as a Driver of Gastric Epithelial Cell Proliferation.Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis YY1 is indispensable for Lgr5+ intestinal stem cell renewal.Concise Review: The Potential Use of Intestinal Stem Cells to Treat Patients with Intestinal Failure.An Inducible, Large-Intestine-Specific Transgenic Mouse Model for Colitis and Colitis-Induced Colon Cancer Research Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.The LRIG family: enigmatic regulators of growth factor receptor signaling.The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele Transcription factor Oct1 is a somatic and cancer stem cell determinant.Localized intestinal radiation and liquid diet enhance survival and permit evaluation of long-term intestinal responses to high dose radiation in mice Krüppel-like Factor 4 Modulates Development of BMI1(+) Intestinal Stem Cell-Derived Lineage Following γ-Radiation-Induced Gut Injury in Mice.Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.Expression of LGR-5, MSI-1 and DCAMKL-1, putative stem cell markers, in the early phases of 1,2-dimethylhydrazine-induced rat colon carcinogenesis: correlation with nuclear β-catenin.BID mediates selective killing of APC-deficient cells in intestinal tumor suppression by nonsteroidal antiinflammatory drugs.Epiprofin orchestrates epidermal keratinocyte proliferation and differentiation Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration.EMT-induced stemness and tumorigenicity are fueled by the EGFR/Ras pathway.Deletion of intestinal epithelial insulin receptor attenuates high-fat diet-induced elevations in cholesterol and stem, enteroendocrine, and Paneth cell mRNAs.Vitamin D is a determinant of mouse intestinal Lgr5 stem cell functions

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The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

http://www.wikidata.org/entity/Q34264864

description

2012 nî lūn-bûn

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2012 թուականի Մարտին հրատարակուած գիտական յօդուած

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2012 թվականի մարտին հրատարակված գիտական հոդված

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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The pan-ErbB negative regulato ...... unctions as a tumor suppressor

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Alwin Juchheim

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Anna L Means

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Anne E Powell

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Emily J Poulin

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James N Higginbotham

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Jeffrey L Franklin

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Kevin M Haigis

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Robert J Coffey

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Yan Guo

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Mapping and quantifying mammalian transcriptomes by RNA-Seq

Accurate whole human genome sequencing using reversible terminator chemistry

LRIG1 and epidermal growth factor receptor in renal cell carcinoma: a quantitative RT--PCR and immunohistochemical analysis

Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy

Inflammation and proliferation act together to mediate intestinal cell fusion

Generalized lacZ expression with the ROSA26 Cre reporter strain

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

Identification of stem cells in small intestine and colon by marker gene Lgr5

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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