Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.
about
Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results.Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cellsThe role of mTOR in memory CD8 T-cell differentiationRapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation.The Pim kinases control rapamycin-resistant T cell survival and activation.Modulation of mTOR Signalling Triggers the Formation of Stem Cell-like Memory T CellsVesicular stomatitis virus oncolysis of T lymphocytes requires cell cycle entry and translation initiation.Paradoxical aspects of rapamycin immunobiology in transplantationRapamycin generates anti-apoptotic human Th1/Tc1 cells via autophagy for induction of xenogeneic GVHDHarnessing autophagy for cell fate control gene therapyTargeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development.Generation of tissue-specific cells from MSC does not require fusion or donor-to-host mitochondrial/membrane transfer.Rapamycin-resistant effector T-cell therapy.Hsp90 inhibition ameliorates CD4(+) T cell-mediated acute Graft versus Host disease in mice.Effect of mTORC1/mTORC2 inhibition on T cell function: potential role in graft-versus-host disease control.
P2860
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P2860
Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@ast
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@en
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@nl
type
label
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@ast
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@en
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@nl
prefLabel
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@ast
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@en
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@nl
P2860
P356
P1476
Rapamycin-resistant proliferat ...... hoinositide 3-kinase activity.
@en
P2093
Dong-Gyun Lim
Jacqueline M Slavik
P2860
P304
P356
10.1074/JBC.M209733200
P407
P577
2003-10-22T00:00:00Z