Cancer chromosomal instability: therapeutic and diagnostic challenges. - Wikidata - awgldk - TriplyDB

Cancer chromosomal instability: therapeutic and diagnostic challenges.

Cancer chromosomal instability: therapeutic and diagnostic challenges.

http://www.wikidata.org/entity/Q34275721

about

Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancer Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates Intratumor heterogeneity: evolution through space and time Tumour heterogeneity and the evolution of polyclonal drug resistance Yeast: a simple model system to study complex phenomena of aneuploidy Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies Genetic alterations in hepatocellular carcinoma: An update Unique features of the transcriptional response to model aneuploidy in human cells Intra-Tumoral Heterogeneity of HER2, FGFR2, cMET and ATM in Gastric Cancer: Optimizing Personalized Healthcare through Innovative Pathological and Statistical Analysis Targeting the adaptability of heterogeneous aneuploids Tracking genomic cancer evolution for precision medicine: the lung TRACERx study The causes and consequences of genetic heterogeneity in cancer evolution Biomarkers of genome instability and cancer epigenetics.Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells.Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway Tumor suppressor protein DAB2IP participates in chromosomal stability maintenance through activating spindle assembly checkpoint and stabilizing kinetochore-microtubule attachments.Detection of Circulating Tumor Cells Using Negative Enrichment Immunofluorescence and an In Situ Hybridization System in Pancreatic Cancer.MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas.TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.Targeting TPX2 Suppresses the Tumorigenesis of Hepatocellular Carcinoma Cells Resulting in Arrested Mitotic Phase Progression and Increased Genomic Instability.Adjusting breast cancer patient prognosis with non-HER2-gene patterns on chromosome 17.Chromosomal instability selects gene copy-number variants encoding core regulators of proliferation in ER+ breast cancer.Cancer heterogeneity: implications for targeted therapeutics.General aspects of colorectal cancer The motor protein KIF14 inhibits tumor growth and cancer metastasis in lung adenocarcinoma Transcriptional consequence and impaired gametogenesis with high-grade aneuploidy in Arabidopsis thaliana Whole genome sequence analysis suggests intratumoral heterogeneity in dissemination of breast cancer to lymph nodes Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution.Comparative oncogenomic analysis of copy number alterations in human and zebrafish tumors enables cancer driver discovery Cyclin B2 and p53 control proper timing of centrosome separation Cancers of unknown primary origin (CUP) are characterized by chromosomal instability (CIN) compared to metastasis of know origin Systematic evaluation of the prognostic impact and intratumour heterogeneity of clear cell renal cell carcinoma biomarkers.Aneuploidy and chromosomal instability in cancer: a jackpot to chaos.Single-Cell Based Quantitative Assay of Chromosome Transmission Fidelity High level of chromosomal instability in circulating tumor cells of ROS1-rearranged non-small-cell lung cancer.Heterogeneous Mechanisms of Secondary Resistance and Clonal Selection in Sarcoma during Treatment with Nutlin.APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.DNA-PKcs Negatively Regulates Cyclin B1 Protein Stability through Facilitating Its Ubiquitination Mediated by Cdh1-APC/C Pathway.A microRNA biomarker of hepatocellular carcinoma recurrence following liver transplantation accounting for within-patient heterogeneity.

P2860

Q21129300-1272D6B8-D31B-4DF6-BD18-101E8D2A8A4A Q24564079-D54602BB-0392-45AC-A626-2AB7AB7098F4 Q24598678-D7D4BE7A-B333-49A4-ACA4-680B0AF27ED2 Q26866803-D29F7EA8-DE77-4526-A79E-9C5E796D6174 Q27001656-298914B6-3C06-4A4D-89E7-9066420BF5A9 Q27311350-8ED1C8FD-368B-4747-BBC4-D051836C2A5B Q27336129-6076474E-B668-4B68-A58C-BCBDE1B5D912 Q28073241-84CF1349-36C9-45FC-AE34-B58F200E4456 Q28396449-DD46EA29-3F06-457C-8682-91CBFC3958E1 Q28551059-2C3140A5-F91D-473C-B34C-15F180B8C686 Q28649939-3E5A3CCD-7219-489E-B7FC-014687AB79D7 Q28655985-5CE219F3-CB53-4247-A1AC-5727E10A3ACB Q29615848-F61348E5-82ED-4F66-923D-38141311AAB5 Q30248745-D420EC36-BF27-43A5-92D1-EF6B9E2BE579 Q30637438-101B1B0B-3FD7-4686-9469-5D575675CD57 Q30781182-BD009039-2D96-4711-9286-40EB6C69F2FB Q30822011-8FB6531D-2CB1-400C-B3EA-A078220CEB93 Q33624194-2A6314A0-7DC4-4E8D-9A7C-AA49E36971B0 Q33657478-0404E389-D94C-46AE-AB3A-F0ECF3A23A47 Q33688803-3071AA2C-BBEC-4436-986B-1E9144C782E6 Q33820856-0D3C4F8F-E4D5-4726-880B-F0970DE7AB4C Q34010867-E09D3A89-1BB1-4BFB-B15A-3FC83BC7009D Q34203984-C3971998-5A7C-4732-8CDD-BBE59BA2D0AC Q34321565-B3BE2DC2-35C7-4BC8-8CCA-A774878CA514 Q34645999-21601A2A-4A2B-4FA8-AAB3-BA8C616B63C2 Q34692260-B8041A34-F444-484A-B4E2-1585C6A3BC68 Q34713097-488164E9-3D34-4A9C-BE7A-ED5221FE9BA1 Q34784863-1468187F-5DDF-46FA-8169-F2DFAAB3D68B Q34946877-42F1F2E5-EFE9-46CB-B529-46921AF6818A Q34979403-11D3265C-B083-45F1-9825-AE80164585F3 Q35232617-618E4DBD-1F61-4E2C-8BFE-DB56C9F7153D Q35503657-B79FE5D0-7D86-482A-BF2D-8CD9CDB20873 Q35540073-7450CF14-2CFD-4442-BC69-CF74FA08FE1C Q35646101-0EA5873F-E6F2-4E0F-824C-6BE172FB14A0 Q35773951-E48D65DA-95EC-472F-94B5-76BAA6DCC5A1 Q35775228-A7ACD21F-8E9B-460E-A76A-F37A63E56D11 Q35795406-F376705D-E9EF-4A09-812A-F4925ACFBA94 Q35836909-CF050F2D-9A54-4D5E-9BAA-F88E6F2FC26B Q35891330-E6112421-7240-4897-ACE3-B0B4F04D984C Q35984012-A468FF59-DFBB-457C-AD0A-79D6F4DF69DA

P2860

Cancer chromosomal instability: therapeutic and diagnostic challenges.

http://www.wikidata.org/entity/Q34275721

description

2012 nî lūn-bûn

@nan

2012 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@ast

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@en

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@nl

type

label

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@ast

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@en

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@nl

prefLabel

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@ast

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@en

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@nl

P1433

Q34275721-4A88846D-4690-44F7-AD9B-75AC17224F8A

P1476

Q34275721-4BD99128-8E85-4798-A039-3FD01B4CF8EB

P2093

Q34275721-003E24D4-119E-477F-91F2-0C225B65FB86

Q34275721-024F452A-61AE-4887-865D-844EA1962E64

Q34275721-76077432-30ED-4284-959E-C7B9AC52B643

P2860

Q34275721-032740C9-9A1B-4444-8057-3C015A750214

Q34275721-0C9BE06E-CF4C-40B5-8972-30C441DFAB7F

Q34275721-0CD64552-E1D1-4E23-AC8B-E9CA49EE1F5E

Q34275721-0F760462-AC58-445B-9DBD-6016F5C79AAD

Q34275721-143260B4-C6AB-48A0-A5F6-B826F6D73A53

Q34275721-165D902B-EC08-4169-AF27-FF9D311C831F

Q34275721-16DE861F-94DF-4A2E-901E-0EEE1ECCF859

Q34275721-17A277F5-D083-4789-828C-7D97D737F52E

Q34275721-17DA16EA-7A13-4123-9601-09537C83D8A2

Q34275721-1887E084-8534-468B-8118-50712691108C

P304

Q34275721-970DE9A4-15C8-4DB2-B1B3-52D58E8097D4

P31

Q34275721-937248F6-6B00-4BAF-8BE2-220EC62CA118

P356

Q34275721-14A3FB83-4D7A-40F9-813A-86900DF77058

P433

Q34275721-35B3A58C-3A98-4179-BE20-3FA3B28C4E30

P478

Q34275721-2010DA1B-40A5-4059-AE35-8480EC76682D

P50

Q34275721-5E74C44B-5481-4D24-A7D4-E9CC0F543A81

Q34275721-DAE059D1-7C99-4761-8EAB-E0A403D753AF

P577

Q34275721-6049DB9F-87CB-46F8-AEDB-E31960B1B31B

P5875

Q34275721-F9515448-6B92-40DD-B024-E85C99201DB4

P698

Q34275721-5369F99A-B087-444B-84A2-F203A2661EA6

P921

Q34275721-767f0ea3-7223-45b2-860c-364fb4e53147

P932

Q34275721-AAC352AB-6383-478C-9E77-0859C6954922

P356

P1433

P1476

Cancer chromosomal instability: therapeutic and diagnostic challenges.

@en

P2093

David Endesfelder

http://www.w3.org/2001/XMLSchema#string

Marco R Novelli

http://www.w3.org/2001/XMLSchema#string

Rebecca A Burrell

http://www.w3.org/2001/XMLSchema#string

P2860

Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint.

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Complex landscapes of somatic rearrangement in human breast cancer genomes.

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Genetic instabilities in human cancers

Genomic instability--an evolving hallmark of cancer

Identification of aneuploidy-tolerating mutations

Tumour evolution inferred by single-cell sequencing

P304

528-538

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/EMBOR.2012.61

http://www.w3.org/2001/XMLSchema#string

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

13

http://www.w3.org/2001/XMLSchema#string

P50

Charles Swanton

Nicholas McGranahan

P577

2012-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

224977765

http://www.w3.org/2001/XMLSchema#string

P698

22595889

http://www.w3.org/2001/XMLSchema#string

P921

P932

3367245

http://www.w3.org/2001/XMLSchema#string